Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

High lethality rates associated with metastatic cancer highlight an urgent medical need for
improved understanding of biologic mechanisms driving metastatic spread and identification …

MicroRNAs are abundant in animal genomes and have been predicted to have important
roles in a broad range of gene expression programmes,. Despite this prominence, there is a …

Recent years have seen much excitement over the possibility that adult mammalian stem
cells may be capable of differentiating across tissue lineage boundaries, and as such may …

Skeletal muscle damaged by injury or by degenerative diseases such as muscular
dystrophy is able to regenerate new muscle fibers. Regeneration mainly depends upon …

Mechanical stimulation (mechanotherapy) can promote skeletal muscle repair, but a lack of
reproducible protocols and mechanistic understanding of the relation between mechanical …

In 1961, the satellite cell was first identified when electron microscopic examination of
skeletal muscle demonstrated a cell wedged between the plasma membrane of the muscle …

Helicobacter infection is the leading cause of gastric cancer worldwide. Infection with this
ubiquitous bacterium incites a chronic active immune response that persists for the life of the …

The muscle satellite cell was first described and actually named on the basis of its anatomic
location under the basement membrane surrounding each myofiber. For many years …