The mechanical properties of cells and tissues help determine their architecture,
composition and function. Alterations to these properties are associated with many diseases …

Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

The outbreak of pandemics (eg, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2 in 2019), influenza A viruses (H1N1 in 2009), etc.), and worldwide spike in the aging …

The cellular microenvironment is influenced explicitly by the extracellular matrix (ECM), the
main tissue support biomaterial, as a decisive factor for tissue growth patterns. The recent …

Cellular phenotypes and functional responses are modulated by the signals present in their
microenvironment, including extracellular matrix (ECM) proteins, tissue mechanical …

The development of therapeutic interventions for diseases necessitates a crucial step known
as drug screening, wherein potential substances with medicinal properties are rigorously …

Industrial cell culture processes are inherently expensive, time-consuming, and variable.
These limitations have become a critical bottleneck for the industrial translation of human …

This systematic review aimed to analyze the development and functionality of microfluidic
concentration gradient generators (CGGs) for toxicological evaluation of different biological …

A multifunctional microfluidic chip integrated with perfusion cell culture and in situ SERS
detection of cell secretion was designed and developed for the detection of IL-6 secretion …

Microfluidic-based neuron cell culture systems have recently gained a lot of attention due to
their efficiency in supporting the spatial and temporal control of cellular microenvironments …