A critical review of the current environmental risks posed by the antidiabetic Metformin and the status, advances, and trends in adsorption technologies for its …

Y Vieira, TH Ribeiro, J Leichtweis, GL Dotto… - Journal of Water …, 2023‏ - Elsevier
The consumption of the antidiabetic drug Metformin (MTFN) has escalated over the last
years due to the worrisome modern sedentary lifestyle. Since MTFN is not metabolized, it …

Zebrafish live imaging: a strong weapon in anticancer drug discovery and development

T Zhan, W Song, G **g, Y Yuan, N Kang… - Clinical and Translational …, 2024‏ - Springer
Develo** anticancer drugs is a complex and time-consuming process. The inability of
current laboratory models to reflect important aspects of the tumor in vivo limits anticancer …

Novel insights into DEHP-induced zebrafish spleen damage: Cellular apoptosis, mitochondrial dysfunction, and innate immunity

L Lyu, Y Tao, K Abaakil, Y Gu, G Zhong, Y Hu… - Science of The Total …, 2024‏ - Elsevier
Abstract DEHP (Di (2-ethylhexyl) phthalate) is the most abundant phthalate component
detected in environmental samples as it is widely used in the manufacturing of children's …

Assessing the toxicity of benzotriazole ultraviolet stabilizers to fishes: Insights into aryl hydrocarbon receptor-mediated effects

HM Johnson, J Dubiel, CH Collins… - Environmental …, 2023‏ - ACS Publications
Benzotriazole ultraviolet stabilizers (BUVSs) are chemicals used to mitigate UV-induced
damage to manufactured goods. Their presence in aquatic environments and biota raises …

Effects of oxidative stress induced by environmental relevant concentrations of fluoxetine on the embryonic development on Danio rerio

JM Orozco-Hernández, LM Gómez-Oliván… - Science of the Total …, 2022‏ - Elsevier
Fluoxetine (FLX) is a psychoactive drug that acts as an antidepressant. FLX is one of the
world's best-selling prescription antidepressants. FLX is widely used for the treatment of …

Assessing the impact of COVID-19 era drug combinations on hepatic functionality: A thorough investigation in adult Danio rerio

DB Onofre-Camarena, GA Elizalde-Velázquez… - Environmental …, 2024‏ - Elsevier
Current and thorough information on the ecotoxicological consequences of pharmaceuticals
is accessible globally. However, there remains a substantial gap in knowledge concerning …

Chronic exposure to realistic concentrations of metformin prompts a neurotoxic response in Danio rerio adults

GA Elizalde-Velázquez, LM Gómez-Oliván… - Science of the Total …, 2022‏ - Elsevier
Metformin (MET) is among the most consumed drugs around the world, and thus, it is
considered the uppermost drug in mass discharged into water settings. Nonetheless, data …

Teratogenic effects induced by paracetamol, ciprofloxacin, and their mixture on Danio rerio embryos: Oxidative stress implications

JR Rosas-Ramírez, JM Orozco-Hernández… - Science of The Total …, 2022‏ - Elsevier
Even though the toxic effects of paracetamol (PCM) and ciprofloxacin (CPX) have been
deeply studied in the last decades, the impact of the PCM-CPX mixture may induce in …

Low concentrations of ciprofloxacin alone and in combination with paracetamol induce oxidative stress, upregulation of apoptotic-related genes, histological …

GA Elizalde-Velázquez, JR Rosas-Ramírez, D Raldua… - Chemosphere, 2022‏ - Elsevier
Nowadays, there are countless articles about the harmful effects of paracetamol (PCM) in
non-target organisms. Nonetheless, information regarding the toxicity of ciprofloxacin (CPX) …

Multi-biomarker approach and IBR index to evaluate the effects of bisphenol A on embryonic stages of zebrafish (Danio rerio)

G Heredia-García, LM Gómez-Oliván… - Environmental …, 2022‏ - Elsevier
This study assessed the effects of Bisphenol A in embryonic stages of zebrafish, applying an
IBR multi-biomarker approach that included alterations in growth and oxidative status and …