The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic

A Shariati, M Arshadi, MA Khosrojerdi… - Frontiers in public …, 2022 - frontiersin.org
For around three decades, the fluoroquinolone (FQ) antibiotic ciprofloxacin has been used
to treat a range of diseases, including chronic otorrhea, endocarditis, lower respiratory tract …

Metabolomics meets systems immunology

J Fu, F Zhu, CJ Xu, Y Li - EMBO reports, 2023 - embopress.org
Metabolic processes play a critical role in immune regulation. Metabolomics is the
systematic analysis of small molecules (metabolites) in organisms or biological samples …

Design, synthesis, structural inspection, and DFT calculation of some novel imine ciprofloxacin metal chelates: A novel approach for pharmaceutical applications and …

AM Abu‐Dief, Y Al‐hawamy, A Abdou… - Applied …, 2024 - Wiley Online Library
Novel compounds with pharmacological activity were synthesized from Pd (II), Fe (III), Cr (III),
Ni (II), and Cu (II) ions with 4‐{2‐(3‐carboxy‐1‐cyclopropyl‐6‐fluoro‐7‐piperazin‐1‐yl‐2, 3 …

Multifunctional Gelatin/Chitosan Electrospun Wound Dressing Dopped with Undaria pinnatifida Phlorotannin-Enriched Extract for Skin Regeneration

CAM Ferreira, AP Januário, R Félix, N Alves… - Pharmaceutics, 2021 - mdpi.com
The similarities of electrospun fibers with the skin extracellular matrix (ECM) make them
promising structures for advanced wound dressings. Moreover, infection and resistance in …

Can we arrest the evolution of antibiotic resistance? The differences between the effects of silver nanoparticles and silver ions

H Zhao, M Wang, Y Cui, C Zhang - Environmental Science & …, 2022 - ACS Publications
Silver nanoparticles (AgNPs) are effective antimicrobial substances that show promise in
combatting multidrug resistance. The potential application and release of AgNPs into the …

Identification of Robust Antibiotic Subgroups by Integrating Multi-Species Drug–Drug Interactions

J Lv, G Liu, Y Ju, H Huang, D Li… - Journal of Chemical …, 2023 - ACS Publications
Previous studies have shown that antibiotics can be divided into groups, and drug–drug
interactions (DDI) depend on their groups. However, these studies focused on a specific …

Comprehensive two-dimensional gas chromatography as a bioanalytical platform for drug discovery and analysis

A Zaid, NH Hassan, PJ Marriott, YF Wong - Pharmaceutics, 2023 - mdpi.com
Over the last decades, comprehensive two-dimensional gas chromatography (GC× GC) has
emerged as a significant separation tool for high-resolution analysis of disease-associated …

Pharmacokinetics of oral ciprofloxacin in adult patients: A sco** review

AM Junkert, REL Lazo, F Deffert… - British Journal of …, 2024 - Wiley Online Library
Aims To map the literature on oral ciprofloxacin's pharmacokinetics and its implications for
dose adjustments in specific populations. Methods A sco** review was performed …

Antibacterial Activity of the Essential Oil From Litsea cubeba Against Cutibacterium acnes and the Investigations of Its Potential Mechanism by Gas Chromatography …

J Chen, J Zhang, L Zhu, C Qian, H Tian… - Frontiers in …, 2022 - frontiersin.org
Cutibacterium acnes (C. acnes) is an anaerobic Gram-positive bacterium generally
considered as a human skin commensal, but is also involved in different infections, such as …

Enhanced Biosynthesis of Fatty Acids Contributes to Ciprofloxacin Resistance in Pseudomonas aeruginosa

Y Su, X Tang, L Zhu, K Yang, L Pan, H Li… - Frontiers in …, 2022 - frontiersin.org
Antibiotic-resistant Pseudomonas aeruginosa is insensitive to antibiotics and difficult to deal
with. An understanding of the resistance mechanisms is required for the control of the …