Darwin's agential materials: evolutionary implications of multiscale competency in developmental biology

M Levin - Cellular and Molecular Life Sciences, 2023 - Springer
A critical aspect of evolution is the layer of developmental physiology that operates between
the genotype and the anatomical phenotype. While much work has addressed the evolution …

Endless forms most beautiful 2.0: teleonomy and the bioengineering of chimaeric and synthetic organisms

WP Clawson, M Levin - Biological Journal of the Linnean …, 2023 - academic.oup.com
The rich variety of biological forms and behaviours results from one evolutionary history on
Earth, via frozen accidents and selection in specific environments. This ubiquitous baggage …

Technological approach to mind everywhere: an experimentally-grounded framework for understanding diverse bodies and minds

M Levin - Frontiers in systems neuroscience, 2022 - frontiersin.org
Synthetic biology and bioengineering provide the opportunity to create novel embodied
cognitive systems (otherwise known as minds) in a very wide variety of chimeric …

Developmental bias and evolution: A regulatory network perspective

T Uller, AP Moczek, RA Watson, PM Brakefield… - Genetics, 2018 - academic.oup.com
A recurrent theme in evolutionary biology is to contrast natural selection and developmental
constraint–two forces pitted against each other as competing explanations for organismal …

There's plenty of room right here: Biological systems as evolved, overloaded, multi-scale machines

J Bongard, M Levin - Biomimetics, 2023 - mdpi.com
There’s Plenty of Room Right Here: Biological Systems as Evolved, Overloaded,
Multi-Scale Machines Next Article in Journal Exploration of the Design of Spiderweb-Inspired …

How can evolution learn?

RA Watson, E Szathmáry - Trends in ecology & evolution, 2016 - cell.com
The theory of evolution links random variation and selection to incremental adaptation. In a
different intellectual domain, learning theory links incremental adaptation (eg, from positive …

The genomic code: The genome instantiates a generative model of the organism

KJ Mitchell, N Cheney - Trends in Genetics, 2024 - cell.com
How does the genome encode the form of the organism? What is the nature of this genomic
code? Inspired by recent work in machine learning and neuroscience, we propose that the …

Cellular signaling pathways as plastic, proto-cognitive systems: Implications for biomedicine

J Mathews, AJ Chang, L Devlin, M Levin - Patterns, 2023 - cell.com
Many aspects of health and disease are modeled using the abstraction of a" pathway"—a
set of protein or other subcellular activities with specified functional linkages between them …

The collective intelligence of evolution and development

R Watson, M Levin - Collective Intelligence, 2023 - journals.sagepub.com
Collective intelligence and individual intelligence are usually considered to be
fundamentally different. Individual intelligence is uncontroversial. It occurs in organisms with …

Defining lyfe in the universe: From three privileged functions to four pillars

S Bartlett, ML Wong - Life, 2020 - mdpi.com
Motivated by the need to paint a more general picture of what life is—and could be—with
respect to the rest of the phenomena of the universe, we propose a new vocabulary for …