Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies
NK Singh, GN Rao - Progress in lipid research, 2019 - Elsevier
lipoxygenase (12/15-LOX) is an enzyme, which oxidizes polyunsaturated fatty acids,
particularly omega-6 and-3 fatty acids, to generate a number of bioactive lipid metabolites. A …
particularly omega-6 and-3 fatty acids, to generate a number of bioactive lipid metabolites. A …
Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease
JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …
Hydroxyoctadecadienoic acids: Oxidised derivatives of linoleic acid and their role in inflammation associated with metabolic syndrome and cancer
VN Vangaveti, H Jansen, RL Kennedy… - European journal of …, 2016 - Elsevier
Linoleic acid (LA) is a major constituent of low-density lipoproteins. An essential fatty acid,
LA is a polyunsaturated fatty acid, which is oxidised by endogenous enzymes and reactive …
LA is a polyunsaturated fatty acid, which is oxidised by endogenous enzymes and reactive …
Regulation of inflammation by selenium and selenoproteins: impact on eicosanoid biosynthesis
SA Mattmiller, BA Carlson, LM Sordillo - Journal of nutritional …, 2013 - cambridge.org
Uncontrolled inflammation is a contributing factor to many leading causes of human
morbidity and mortality including atherosclerosis, cancer and diabetes. Se is an essential …
morbidity and mortality including atherosclerosis, cancer and diabetes. Se is an essential …
Integrated transcriptomic and metabolomic analysis of cultivar differences provides insights into the browning mechanism of fresh-cut potato tubers
L Qiao, M Gao, Y Wang, X Tian, L Lu, X Liu - Postharvest Biology and …, 2022 - Elsevier
The quality of fresh-cut potato tubers is usually impacted by surface browning, which affects
food quality. Here, four potato cultivars that differed in their sensitivity to postcutting browning …
food quality. Here, four potato cultivars that differed in their sensitivity to postcutting browning …
Metabolomic identification of serum exosome‐derived biomarkers for bipolar disorder
Y Du, JH Dong, L Chen, H Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Background. Exosomes are extracellular vesicles that play important roles in various
physiological and pathological functions. Previous studies have demonstrated that exosome …
physiological and pathological functions. Previous studies have demonstrated that exosome …
Rat hair metabolomics analysis reveals perturbations of unsaturated fatty acid biosynthesis, phenylalanine, and arachidonic acid metabolism pathways are associated …
TH Tan, SW Li, CW Chang, YC Chen, YH Liu… - Molecular …, 2023 - Springer
Hair is a noninvasive valuable biospecimen for the long-term assessment of endogenous
metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the …
metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the …
[HTML][HTML] Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling
Almost invariably, humans become ill during primary infections with malaria parasites which
is a pathology associated with oxidative stress and perturbations in metabolism. Importantly …
is a pathology associated with oxidative stress and perturbations in metabolism. Importantly …
Bioactive lipids accumulate in stored red blood cells despite leukoreduction: a targeted metabolomics study
X Fu, JR Felcyn, K Odem‐Davis, JC Zimring - Transfusion, 2016 - Wiley Online Library
BACKGROUND Accumulation of bioactive lipids during red blood cell (RBC) storage has
been identified as a potential source of posttransfusion sequelae in vulnerable populations …
been identified as a potential source of posttransfusion sequelae in vulnerable populations …
Anti-Biofilm Activity of Carnosic Acid from Salvia rosmarinus against Methicillin-Resistant Staphylococcus aureus
The Salvia rosmarinus “Eretto Liguria” ecotype was studied as a source of valuable
bioactive compounds. LC-MS analysis of the methanolic extract underlined the presence of …
bioactive compounds. LC-MS analysis of the methanolic extract underlined the presence of …