Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

A variety of chemical substances used in plastic production may be released throughout the
entire life cycle of the plastic, posing risks to human health, the environment, and recycling …

Global plastics production has reached 380 million metric tons in 2015, with around 40%
used for packaging. Plastic packaging is diverse and made of multiple polymers and …

Toxicology is undergoing a digital revolution, with mobile apps, sensors, artificial
intelligence (AI), and machine learning enabling better record-kee**, data analysis, and …

Despite an abundance of online databases providing access to chemical data, there is
increasing demand for high-quality, structure-curated, open data to meet the various needs …

Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …

The collection of chemical structure information and associated experimental data for
quantitative structure–activity/property relationship (QSAR/QSPR) modeling is facilitated by …

The US Environmental Protection Agency's (EPA) ToxCast program is testing a large library
of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to …

Quantitative data on product chemical composition is a necessary parameter for
characterizing near-field exposure. This data set comprises reported and predicted …

Use of high-throughput, in vitro bioactivity data in setting a point-of-departure (POD) has the
potential to accelerate the pace of human health safety evaluation by informing screening …