Advances in radiation techniques have enabled the precise delivery of higher doses of
radiotherapy to tumours, while sparing surrounding healthy tissues. Consequently, the …

This review explores the mechanisms of chronic radiation-induced skin injury fibrosis,
focusing on the transition from acute radiation damage to a chronic fibrotic state. It reviewed …

Simple Summary Dose and efficacy of radiation therapy are limited by the toxicity to normal
tissue adjacent to the treated tumor region. Recently, ultra-high dose rate radiotherapy …

Patients undergoing radiation therapy for head and neck cancer (HNC) experience
significant early and long-term side effects. The likelihood and severity of complications …

Background Breast reconstruction is the mainstay treatment choice for patients subjected to
a mastectomy. Prepectoral implant-based breast reconstruction (IBBR) is deemed to be a …

Fibrosis is a common pathological process that can affect virtually all the organs, but there
are hardly any effective therapeutic options. This has led to an intense search for antifibrotic …

Background This study aimed to investigate skin condition, quality of life, and psychological
impact of breast cancer patients after radiation therapy. We designed and administered a …

When dysregulated, skin fibrosis can lead to a multitude of pathologies. We provide a
framework for understanding the wide clinical spectrum, mechanisms, and management of …

Importance Previous studies have suggested that radiation therapy may contribute to an
increased risk of subsequent nonkeratinocyte (ie, not squamous and basal cell) skin …

Caffeic acid (CA) is a polyphenol belonging to the phenylpropanoid family, commonly found
in plants and vegetables. It was first identified by Hlasiwetz in 1867 as a breakdown product …