Recent developments in synthetic biology, combined with continued progress in systems
biology and metabolic engineering, have enabled the engineering of microorganisms to …

Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Background Estimation of the number and rate of deaths by age and sex is a key first stage
for calculation of the burden of disease in order to constrain estimates of cause-specific …

Background Over the past decade malaria intervention coverage has been scaled up across
Africa. However, it remains unclear what overall reduction in transmission is achievable …

Falciparum malaria persists in hard-to-reach areas or demographic groups that are missed
by conventional healthcare systems but could be reached by trained community members in …

This article gives an overview of some of the ongoing challenges that are faced in the
prevention, diagnosis and treatment of malaria. Malaria causes approximately 881,000 …

Background. Parasite clearance time after artemisinin-based combination therapy (ACT)
may be increasing in Asian and African settings. The association between parasite …

Background. Artemisinin-based combination therapy (ACT) reduces the potential for malaria
transmission, compared with non-ACTs. It is unclear whether this effect differs between …

Contact tracking is one of the key technologies in prevention and control of infectious
diseases. In the face of a sudden infectious disease outbreak, contact tracking systems can …

Introduction: Malaria is a devastating vector-borne disease caused by the Plasmodium
parasite, resulting in almost 0.5 million casualties per year. The parasite has a complex life …