[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

Phytochemical-loaded liposomes for anticancer therapy: an updated review

VP Chavda, D Vihol, B Mehta, D Shah, M Patel… - …, 2022 - Taylor & Francis
The major obstacles observed in current chemotherapy are severe adverse effects, narrow
therapeutic indexes and multidrug resistance. Anticancer phytochemicals are extracted and …

Advanced phytochemical-based nanocarrier systems for the treatment of breast cancer

VP Chavda, LV Nalla, P Balar, R Bezbaruah… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a concern for the healthcare system. Even with the
advancement of science and technology, the current system for therapeutics and diagnostics …

Cellular and molecular mechanisms underlying the potential of betulinic acid in cancer prevention and treatment

S Banerjee, S Banerjee, A Bishayee, MN Da Silva… - Phytomedicine, 2024 - Elsevier
Background Betulinic acid (BA), which is a pentacyclic triterpenoid found in the bark of
plane, birch, and eucalyptus trees, has emerged as a compound of significant interest in …

Surface engineering of magnetic iron oxide nanoparticles for breast cancer diagnostics and drug delivery

M **e, F Meng, P Wang, AM Díaz-García… - International Journal …, 2024 - Taylor & Francis
Data published in 2020 by the International Agency for Research on Cancer (IARC) of the
World Health Organization show that breast cancer (BC) has become the most common …

Biosynthesis of iron oxide nanoparticles: Physico-chemical characterization and their In vitro cytotoxicity on healthy and tumorigenic cell lines

EA Moacă, CG Watz, C Păcurariu, LB Tudoran… - Nanomaterials, 2022 - mdpi.com
Iron oxide nanoparticles were synthesized starting from two aqueous extracts based on
Artemisia absinthium L. leaf and stems, employing a simplest, eco-friendliness and low …

Nanoparticulate drugs and vaccines: breakthroughs and bottlenecks of repurposing in breast cancer

P Kumbhar, K Kole, V Khadake, P Marale… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is a highly diagnosed and topmost cause of death in females worldwide.
Drug repurposing (DR) has shown great potential against BC by overcoming major …

Assessment of betulinic acid cytotoxicity and mitochondrial metabolism impairment in a human melanoma cell line

D Coricovac, CA Dehelean, I Pinzaru, A Mioc… - International Journal of …, 2021 - mdpi.com
Melanoma represents one of the most aggressive and drug resistant skin cancers with poor
prognosis in its advanced stages. Despite the increasing number of targeted therapies …

Recent advances in the development of multifunctional lipid-based nanoparticles for co-delivery, combination treatment strategies, and theranostics in breast and lung …

YS Loo, NI Zahid, T Madheswaran, IDM Azmi - Journal of Drug Delivery …, 2022 - Elsevier
Cancer nanomedicines and the development of state-of-the-art multifunctional lipid-based
nanoparticles (NPs) has become a fundamental resource in resolving challenging …