Human immunoglobulin preparations for intravenous or subcutaneous administration are
the cornerstone of treatment in patients with primary immunodeficiency diseases affecting …

Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the
serum of thousands of donors and were initially used as an IgG replacement therapy in …

Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which …

The remarkable success story of the therapeutic application of pooled immunoglobulin G
(IgG) preparations from thousands of donors, the so-called intravenous IgG (IVIG) therapy, to …

For many years, programmed cell death, known as apoptosis, was attributed exclusively to
nucleated cells. Currently, however, apoptosis is also well-documented in anucleate …

Interaction between target cell CD47 and the inhibitory macrophage receptor signal
regulatory protein α (SIRPα) counteracts macrophage phagocytosis of CD47-expressing …

Despite a more than 20-year experience of therapeutic benefit, the relevant molecular and
cellular targets of intravenous immunoglobulin (IVIg) in autoimmune disease remain …

Background: The mechanisms responsible for thrombocytopenia associated with dengue
fever (DF) and dengue hemorrhage fever (DHF) remain unclear. Objective: In this study, we …

Inflammatory responses to cell-associated or tissue-associated immune complexes are key
elements in the pathogenesis of several autoimmune diseases, including rheumatoid …

Immunoglobulin G (IgG) molecules can have two completely opposite functions. On one
hand, they induce proinflammatory responses and recruit innate immune effector cells …