Highlights•Drug-likeness refers to the similarity between compounds and drugs; drug-like
compounds are more likely to be transformed into drugs.•Chemical structures with enhanced …

Natural products are continually explored in the development of new bioactive compounds
with industrial applications, attracting the attention of scientific research efforts due to their …

Controllable and on‐demand delivery of supramolecular systems have received
considerable attention in modern agricultural management, especially for managing …

As part of a program to discover novel succinate dehydrogenase inhibitor fungicides, a
series of new pyrazole acyl (thio) urea compounds containing a diphenyl motif were …

It is important to discover new pesticides with new modes of action because of the
increasing evolution of pesticide resistance. In this study, a series of novel pyrimidin-4 …

Poor bioavailability of pesticides is one of the major bottlenecks in the development of
pesticides. Applications of the concept of pesticide-likeness have been widely accepted as …

A total of 22 quinazoline thioether derivatives incorporating a 1, 2, 4-triazolo [4, 3-a] pyridine
moiety were designed, synthesized, and evaluated as antimicrobial agents in agriculture …

A series of novel 2-Ar-1, 2, 3-triazole derivatives were designed and synthesized based on
our previously discovered active compound 6d against Rhizoctonia solani. Most of these …

Thirty novel dioxolane ring compounds were designed and synthesized. Their chemical
structures were confirmed by 1H NMR, HRMS, and single crystal X-ray diffraction analysis …

Drug discovery, which plays a vital role in maintaining human health, is a persistent
challenge. Fragment-based drug discovery (FBDD) is one of the strategies for the discovery …