Controlled propulsion of micro/nanomotors: operational mechanisms, motion manipulation and potential biomedical applications

T Liu, L **e, CAH Price, J Liu, Q He… - Chemical Society Reviews, 2022 - pubs.rsc.org
Inspired by natural mobile microorganisms, researchers have developed micro/nanomotors
(MNMs) that can autonomously move by transducing different kinds of energies into kinetic …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Urease-powered nanobots for radionuclide bladder cancer therapy

C Simó, M Serra-Casablancas, AC Hortelao… - Nature …, 2024 - nature.com
Bladder cancer treatment via intravesical drug administration achieves reasonable survival
rates but suffers from low therapeutic efficacy. To address the latter, self-propelled …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

Medical micro/nanorobots in complex media

Z Wu, Y Chen, D Mukasa, OS Pak, W Gao - Chemical Society Reviews, 2020 - pubs.rsc.org
Medical micro/nanorobots have received tremendous attention over the past decades owing
to their potential to be navigated into hard-to-reach tissues for a number of biomedical …

Micro‐/nanorobots at work in active drug delivery

M Luo, Y Feng, T Wang, J Guan - Advanced Functional …, 2018 - Wiley Online Library
After the tremendous advances over the past two decades, micro‐/nanorobots can
effectively convert other forms of energy into propulsion and movement, as well as be …

Micro/nanomotors towards in vivo application: cell, tissue and biofluid

F Peng, Y Tu, DA Wilson - Chemical Society Reviews, 2017 - pubs.rsc.org
Inspired by highly efficient natural motors, synthetic micro/nanomotors are self-propelled
machines capable of converting the supplied fuel into mechanical motion. A significant …

Deep penetration of nanolevel drugs and micrometer-level T cells promoted by nanomotors for cancer immunochemotherapy

H Chen, T Shi, Y Wang, Z Liu, F Liu… - Journal of the …, 2021 - ACS Publications
The ability of nanomotors to promote the deep penetration of themselves and the loaded
drugs in diseased tissues has been proposed and confirmed. However, whether such …

Collective behaviors of active matter learning from natural taxes across scales

F Ji, Y Wu, M Pumera, L Zhang - Advanced Materials, 2023 - Wiley Online Library
Taxis orientation is common in microorganisms, and it provides feasible strategies to
operate active colloids as small‐scale robots. Collective taxes involve numerous units that …

Light-triggered mechanical disruption of extracellular barriers by swarms of enzyme-powered nanomotors for enhanced delivery

JC Fraire, M Guix, AC Hortelao, N Ruiz-González… - ACS …, 2023 - ACS Publications
Targeted drug delivery depends on the ability of nanocarriers to reach the target site, which
requires the penetration of different biological barriers. Penetration is usually low and slow …