The self-organization of cells relies on the profound complexity of protein-protein
interactions. Challenges in directly observing these events have hindered progress toward …

It is often assumed in biophysical studies that when multiple identical molecular motors
interact with two parallel microtubules, the microtubules will be crosslinked and locked …

Fluid-resistance limited transport of vesicles through narrow constrictions is a recurring
theme in many biological and engineering applications. Inspired by the motor-driven …

Even though most axonal cargos are synthesized in the soma, the concentration of many of
these cargos is larger at the presynaptic terminal than in the soma. This requires transport of …

This study investigates the development of intricate pattern formation in synaptogenesis,
which describes the transfer of synapses between neurons via bidirectional active and …

We propose a general mathematical and computational approach to study cellular transport
driven by a group of kinesin motors. It is a framework for multi-scale modeling that integrates …

The self-organization of cells relies on the profound complexity of protein-protein
interactions. Challenges in directly observing these events have hindered progress toward …

Intracellular transport is the process by which cargoes, such as organelles, travel to their
needed locations within the cell in a timely manner via cytoskeletal filaments. This process …

We propose a general framework for studying statistics of jump-diffusion systems driven by
both Brownian noise (diffusion) and a jump process with state-dependent intensity. Of …