Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …

An increasing number of studies highlight the role of mutant p53 proteins in cancer cell
growth and in the worsening of cancer patients' clinical outcome. Autophagy has been …

Mutations in TP53 gene play a pivotal role in tumorigenesis and cancer development. Here,
we report that gain-of-function mutant p53 proteins inhibit the autophagic pathway favoring …

Background Deregulations of long non-coding RNAs (lncRNAs) have been implicated in
cancer initiation and progression. Current methods can only capture differential expression …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

Background: Autophagy plays an important role in lung adenocarcinoma (LUAD). In this
study, we aimed to explore the autophagy-related gene (ARG) expression pattern and to …

Transcription cofactor Yes-associated protein (YAP) plays an important role in cancer
progression. Here, we found that Aurora A kinase expression was positively correlated with …

Target-specific treatment modalities are currently not available for triple-negative breast
cancer (TNBC), and acquired chemotherapy resistance is a primary obstacle for the …

Background The purpose of this study is to perform bioinformatics analysis of autophagy-
related genes in gastric cancer, and to construct a multi-gene joint signature for predicting …

Carcinogenesis is a multifactorial process with the input and interactions of environmental,
genetic, and metabolic factors. During cancer development, a significant remodeling of the …