Protein film electrochemistry (PFE) has given unrivalled insight into the properties of redox
proteins and many electron-transferring enzymes, allowing investigations of otherwise ill …

Natural cascades frequently use spatial organization to introduce beneficial substrate
channeling mechanisms, a strategy that has been widely mimicked in many engineered …

Substrate channeling, where an intermediate in a multistep reaction is directed toward a
reaction center rather than freely diffusing, offers several advantages when employed in …

Millions of years of evolution have optimized many biosynthetic pathways by use of multi‐
step catalysis. In addition, multi‐step metabolic pathways are commonly found in and on …

The natural ability of many proteins to polymerize into highly structured filaments has been
harnessed as scaffolds to align functional molecules in a diverse range of biomaterials …

Queueing approaches can capture the stochastic dynamics of chemical reactions and
provide a more accurate picture of the reaction kinetics than coupled differential equations in …

The multienzymatic reaction in bioelectrocatalytic systems can offer promising pathways for
diverse biochemical synthesis or higher electricity generation. To achieve efficient enzymatic …

In this opinion paper, we discuss the charge transfer at biotic/abiotic interfaces in man-made
and biological electrochemical systems. Specifically, we will first introduce the …

Electrostatic channeling is a naturally occurring approach to control the flux of charged
intermediates in catalytic cascades. Computational techniques have enabled quantitative …

In biological systems, the majority of chemistry occurs in enzymatic pathways. Pathways are
essentially cascades of protein catalysts used for catabolism or metabolism. However, in …