Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review
KS Nitsche, I Müller, S Malcomber, PL Carmichael… - Archives of …, 2022 - Springer
Abstract Organ-on-chip (OoC) technology is full of engineering and biological challenges,
but it has the potential to revolutionize the Next-Generation Risk Assessment of novel …
but it has the potential to revolutionize the Next-Generation Risk Assessment of novel …
Bioprinting technologies in tissue engineering
Bioprinting technology is a strong tool in producing living functional tissues and organs from
cells, biomaterial-based bioinks, and growth factors in computer-controlled platform. The aim …
cells, biomaterial-based bioinks, and growth factors in computer-controlled platform. The aim …
Cultivating complexity: Advancements in establishing in vitro models for the mucus‐adhering gut microbiota
M Calvigioni, D Mazzantini, F Celandroni… - Microbial …, 2024 - Wiley Online Library
A healthy mucus is essential for maintaining intestinal homeostasis and overall well‐being.
In recent years, extensive research focused on understanding the intricate interactions …
In recent years, extensive research focused on understanding the intricate interactions …
[HTML][HTML] Toward better drug development: Three-dimensional bioprinting in toxicological research
D Szűcs, Z Fekete, M Guba, L Kemény… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
The importance of three-dimensional (3D) models in pharmacological tests and
personalized therapies is significant. These models allow us to gain insight into the cell …
personalized therapies is significant. These models allow us to gain insight into the cell …
3D Bioprinting for fabrication of tissue models of COVID-19 infection
A Kabir, P Datta, J Oh, A Williams… - Essays in …, 2021 - portlandpress.com
Over the last few decades, the world has witnessed multiple viral pandemics, the current
severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic being …
severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic being …
Development of rat duodenal monolayer model with effective barrier function from rat organoids for ADME assay
K Tanaka, S Kawai, E Fujii, M Yano, T Miyayama… - Scientific Reports, 2023 - nature.com
The in-depth analysis of the ADME profiles of drug candidates using in vitro models is
essential for drug development since a drug's exposure in humans depends on its ADME …
essential for drug development since a drug's exposure in humans depends on its ADME …
[HTML][HTML] Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug disposition
PGM Canhão, J Snoeys, S Geerinckx… - European Journal of …, 2025 - Elsevier
The purpose of this study was to evaluate EpiColon, a novel human organotypic 3D colon
microtissue prototype, developed to assess colonic drug disposition, with a particular focus …
microtissue prototype, developed to assess colonic drug disposition, with a particular focus …
Set Up and Utilization of a Three‐Dimensional In Vitro Bioreactor System for Human Intestinal Studies and Microbial Co‐Cultures
SE Rudolph, E Bethi, L Iglesias‐Ledon… - Current …, 2024 - Wiley Online Library
The study of human intestinal physiology and host‐microbe interactions is crucial for
understanding gastrointestinal health and disease. Traditional two‐dimensional cell culture …
understanding gastrointestinal health and disease. Traditional two‐dimensional cell culture …
[HTML][HTML] Advancements in 3D bioprinting for precision medicine: Enhancing patient-derived organoids and extracellular vesicle applications in inflammatory diseases
The integration of three-dimensional (3D) bioprinting with cultures of patient-derived
organoids represents a transformative advancement in precision medicine, enabling the …
organoids represents a transformative advancement in precision medicine, enabling the …
[HTML][HTML] Advances of 3D printing in gastroenterology and where it might be going
Y Zhang, L Chen, B Hu - International Journal of Bioprinting, 2023 - accscience.com
Gastrointestinal (GI) system comprises a great number of organs and tissues of various
functions, both hollow and solid. However, it is still a less well-developed area for three …
functions, both hollow and solid. However, it is still a less well-developed area for three …