[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022‏ - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Antibiotic resistance and the MRSA problem

M Vestergaard, D Frees, H Ingmer - Microbiology spectrum, 2019‏ - journals.asm.org
Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

Antibiotic resistance in Staphylococcus aureus. Current status and future prospects

TJ Foster - FEMS microbiology reviews, 2017‏ - academic.oup.com
The major targets for antibiotics in staphylococci are (i) the cell envelope,(ii) the ribosome
and (iii) nucleic acids. Several novel targets emerged from recent targeted drug discovery …

Antibacterial drug discovery in the resistance era

ED Brown, GD Wright - Nature, 2016‏ - nature.com
The looming antibiotic-resistance crisis has penetrated the consciousness of clinicians,
researchers, policymakers, politicians and the public at large. The evolution and widespread …

Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection

G Qing, X Zhao, N Gong, J Chen, X Li, Y Gan… - Nature …, 2019‏ - nature.com
New strategies with high antimicrobial efficacy against multidrug-resistant bacteria are
urgently desired. Herein, we describe a smart triple-functional nanostructure, namely …

Actinomycetes: still a source of novel antibiotics

O Genilloud - Natural product reports, 2017‏ - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

Prospects for new antibiotics: a molecule-centered perspective

CT Walsh, TA Wencewicz - The Journal of antibiotics, 2014‏ - nature.com
There is a continuous need for iterative cycles of antibiotic discovery and development to
deal with the selection of resistant pathogens that emerge as therapeutic application of an …

Penicillin‐binding protein 2a of methicillin‐resistant Staphylococcus aureus

J Fishovitz, JA Hermoso, M Chang, S Mobashery - IUBMB life, 2014‏ - Wiley Online Library
High‐level resistance to β‐lactam antibiotics in methicillin‐resistant Staphylococcus aureus
(MRSA) is due to expression of penicillin‐binding protein 2a (PBP2a), a transpeptidase that …

[ספר][B] Practical handbook of microbiology

LH Green, E Goldman - 2021‏ - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Insights into the structure, function, and dynamics of the bacterial cytokinetic FtsZ-ring

R McQuillen, J **ao - Annual Review of Biophysics, 2020‏ - annualreviews.org
The FtsZ protein is a highly conserved bacterial tubulin homolog. In vivo, the functional form
of FtsZ is the polymeric, ring-like structure (Z-ring) assembled at the future division site …