Nanoparticles and targeted drug delivery in cancer therapy

B Bahrami, M Hojjat-Farsangi, H Mohammadi… - Immunology letters, 2017 - Elsevier
Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Application of biomedical materials in the diagnosis and treatment of myocardial infarction

J Zhang, Y Guo, Y Bai, Y Wei - Journal of nanobiotechnology, 2023 - Springer
Myocardial infarction (MI) is a cardiovascular emergency and the leading cause of death
worldwide. Inflammatory and immune responses are initiated immediately after MI, leading …

Histology and gadolinium distribution in the rodent brain after the administration of cumulative high doses of linear and macrocyclic gadolinium-based contrast agents

J Lohrke, AL Frisk, T Frenzel, L Schöckel… - Investigative …, 2017 - journals.lww.com
Objectives Retrospective studies in patients with primary brain tumors or other central
nervous system pathologies as well as postmortem studies have suggested that gadolinium …

Hybrid protein-inorganic nanoparticles: from tumor-targeted drug delivery to cancer imaging

AO Elzoghby, AL Hemasa, MS Freag - Journal of Controlled Release, 2016 - Elsevier
Recently, a great interest has been paid to the development of hybrid protein-inorganic
nanoparticles (NPs) for drug delivery and cancer diagnostics in order to combine the merits …

[HTML][HTML] Polymeric nanoparticles in the diagnosis and treatment of myocardial infarction: Challenges and future prospects

M Karam, D Fahs, B Maatouk, B Safi, AA Jaffa… - Materials Today Bio, 2022 - Elsevier
Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide. Despite
extensive efforts to provide early diagnosis and adequate treatment regimens, detection of …

Functional nanoparticles in targeting glioma diagnosis and therapies

M Li, H Deng, H Peng, Q Wang - Journal of nanoscience and …, 2014 - ingentaconnect.com
Successful therapy and diagnosis of glioma is one of the biggest challenges in the
biomedical fields. The incidence is growing gradually around the world. Annually, there are …

Targeted diagnostic magnetic nanoparticles for medical imaging of pancreatic cancer

I Rosenberger, A Strauss, S Dobiasch, C Weis… - Journal of controlled …, 2015 - Elsevier
Highly aggressive cancer types such as pancreatic cancer possess a mortality rate of up to
80% within the first 6 months after diagnosis. To reduce this high mortality rate, more …

Protein-Engineered Nanoscale Micelles for Dynamic 19F Magnetic Resonance and Therapeutic Drug Delivery

LK Hill, JA Frezzo, P Katyal, DM Hoang… - ACS …, 2019 - ACS Publications
Engineered proteins provide an interesting template for designing fluorine-19 (19F)
magnetic resonance imaging (MRI) contrast agents, yet progress has been hindered by the …

Biofunctionalized gadolinium-containing prussian blue nanoparticles as multimodal molecular imaging agents

MF Dumont, HA Hoffman, PRS Yoon… - Bioconjugate …, 2014 - ACS Publications
Molecular imaging agents enable the visualization of phenomena with cellular and
subcellular level resolutions and therefore have enormous potential in improving disease …

Assessment of the pharmacokinetics, disposition, and duration of action of the tumour-targeting peptide CEND-1

HA Järveläinen, C Schmithals, M von Harten… - International Journal of …, 2023 - mdpi.com
CEND-1 (iRGD) is a bifunctional cyclic peptide that can modulate the solid tumour
microenvironment, enhancing the delivery and therapeutic index of co-administered anti …