Over time, the human DNA methylation landscape accrues substantial damage, which has
been associated with a broad range of age-related diseases, including cardiovascular …

Complex multicellular organisms, such as mammals, express two complete sets of
chromosomes per nucleus, combining the genetic material of both parents. However …

The human circadian system has a period of approximately 24 h and studies on the
consequences of “chornodisruption” have greatly expanded. Lifestyle and environmental …

Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Patterns of daily human activity are controlled by an intrinsic circadian clock that promotes∼
24 hr rhythms in many behavioral and physiological processes. This system is altered in …

Chronotherapeutics aim at treating illnesses according to the endogenous biologic rhythms,
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …

Seasonal variations are rarely considered a contributing component to human tissue
function or health, although many diseases and physiological process display annual …

Daily rhythms in behavior, physiology, and metabolism are an integral part of homeostasis.
These rhythms emerge from interactions between endogenous circadian clocks and …

Daylight stems solely from direct, scattered and reflected sunlight, and undergoes dynamic
changes in irradiance and spectral power composition due to latitude, time of day, time of …

Human activities have caused a near-ubiquitous and evolutionarily-unprecedented increase
in environmental sound levels and artificial night lighting. These stimuli reorganize …