The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response

J Fraszczak, T Möröy - Advances in immunology, 2021 - Elsevier
Abstract GFI1 and GFI1B are small nuclear proteins of 45 and 37 kDa, respectively, that
have a simple two-domain structure: The first consists of a group of six c-terminal C 2 H 2 …

[HTML][HTML] Novel, Non–Gene-Destructive Knock-In Reporter Mice Refute the Concept of Monoallelic Gata3 Expression

TN Rao, S Kumar, AJ Pulikkottil, F Oliveri… - The Journal of …, 2020 - journals.aai.org
Accurately tuned expression levels of the transcription factor GATA-3 are crucial at several
stages of T cell and innate lymphoid cell development and differentiation. Moreover, several …

High-throughput single-cell sequencing of both TCR-β alleles

T Hosoya, H Li, CJ Ku, Q Wu, Y Guan… - The Journal of …, 2018 - journals.aai.org
Allelic exclusion is a vital mechanism for the generation of monospecificity to foreign Ags in
B and T lymphocytes. In this study, we developed a high-throughput barcoded method to …

[BOEK][B] Endothelial Heterogeneity: A Role for Epigenetic Pathways in Constitutive Gene Expression

L Chen - 2019 - search.proquest.com
Endothelial cells (ECs) have distinct gene expression and morphology depending on their
location in the vasculature. A prevailing assumption is that these differences are largely …

High throughput single cell sequencing of both T-cell-receptor-beta alleles

T Hosoya, H Li, CJ Ku, Q Wu, Y Guan, JD Engel - bioRxiv, 2018 - biorxiv.org
Allelic exclusion is a vital mechanism for the generation of monospecificity to foreign
antigens in B-and T-lymphocytes. Here we developed a high-throughput barcoded method …