Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

During spaceflight, the central nervous system (CNS) is exposed to a complex array of
environmental stressors. However, the effects of long-duration spaceflight on the CNS and …

Long-duration spaceflight induces detrimental changes in human physiology. Its residual
effects and mechanisms remain unclear. We prospectively investigated the changes in …

As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Background Astronauts on long-duration spaceflight missions may develop changes in
ocular structure and function, which can persist for years after the return to normal gravity …

Astronauts are required to maintain optimal neurobehavioral functioning despite chronic
exposure to the stressors and challenges of spaceflight. Sleep of adequate quality and …

BACKGROUND AND PURPOSE: Widespread brain structural changes are seen following
extended spaceflight missions. The purpose of this study was to investigate whether these …

Long-duration spaceflight causes widespread physiological changes, although its effect on
brain structure remains poorly understood. In this work, we acquired diffusion magnetic …