Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation

R Wu, R **ong, Y Li, J Chen, R Yan - Journal of autoimmunity, 2023 - Elsevier
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …

The role of gut microbiota in T cell immunity and immune mediated disorders

JA Shim, JH Ryu, Y Jo, C Hong - International journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Gut microbiota was only considered as a commensal organism that aids in digestion, but
recent studies revealed that the microbiome play a critical role in both physiological and …

Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis

TM Halsey, AS Thomas, T Hayase, W Ma… - Science translational …, 2023 - science.org
Immune checkpoint inhibitors (ICIs) target advanced malignancies with high efficacy but also
predispose patients to immune-related adverse events like immune-mediated colitis (IMC) …

Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration

S Priya, MB Burns, T Ward, RAT Mars… - Nature …, 2022 - nature.com
While gut microbiome and host gene regulation independently contribute to gastrointestinal
disorders, it is unclear how the two may interact to influence host pathophysiology. Here we …

Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion

M Zhu, H Xu, Y Liang, J Xu, N Yue, Y Zhang… - Journal of …, 2023 - Springer
Plant-derived exosome-like nanoparticles (PDENs) have been paid great attention in the
treatment of ulcerative colitis (UC). As a proof of concept, we isolated and identified …

[PDF][PDF] Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired infections and enhance immunity

AO Olatunji, JA Olaboye, CC Maha… - International Medical …, 2024 - researchgate.net
Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired
infections and enhance immuni Page 1 International Medical Science Research Journal, Volume 4 …

Systematic review: the gut microbiome and its potential clinical application in inflammatory bowel disease

L Aldars-Garcia, M Chaparro, JP Gisbert - Microorganisms, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …

Guild-based analysis for understanding gut microbiome in human health and diseases

G Wu, N Zhao, C Zhang, YY Lam, L Zhao - Genome medicine, 2021 - Springer
To demonstrate the causative role of gut microbiome in human health and diseases, we first
need to identify, via next-generation sequencing, potentially important functional members …

The diagnostic and prognostic potential of gut bacteria in inflammatory bowel disease

DK Wiredu Ocansey, S Hang, X Yuan, H Qian… - Gut …, 2023 - Taylor & Francis
The gut microbiome serves as a signaling hub that integrates environmental inputs with
genetic and immune signals to influence the host's metabolism and immunity. Gut bacteria …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …