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Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …
common gastrointestinal diseases. The microbial communities play essential roles in host …
The role of gut microbiota in T cell immunity and immune mediated disorders
JA Shim, JH Ryu, Y Jo, C Hong - International journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Gut microbiota was only considered as a commensal organism that aids in digestion, but
recent studies revealed that the microbiome play a critical role in both physiological and …
recent studies revealed that the microbiome play a critical role in both physiological and …
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis
TM Halsey, AS Thomas, T Hayase, W Ma… - Science translational …, 2023 - science.org
Immune checkpoint inhibitors (ICIs) target advanced malignancies with high efficacy but also
predispose patients to immune-related adverse events like immune-mediated colitis (IMC) …
predispose patients to immune-related adverse events like immune-mediated colitis (IMC) …
Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration
While gut microbiome and host gene regulation independently contribute to gastrointestinal
disorders, it is unclear how the two may interact to influence host pathophysiology. Here we …
disorders, it is unclear how the two may interact to influence host pathophysiology. Here we …
Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion
M Zhu, H Xu, Y Liang, J Xu, N Yue, Y Zhang… - Journal of …, 2023 - Springer
Plant-derived exosome-like nanoparticles (PDENs) have been paid great attention in the
treatment of ulcerative colitis (UC). As a proof of concept, we isolated and identified …
treatment of ulcerative colitis (UC). As a proof of concept, we isolated and identified …
[PDF][PDF] Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired infections and enhance immunity
Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired
infections and enhance immuni Page 1 International Medical Science Research Journal, Volume 4 …
infections and enhance immuni Page 1 International Medical Science Research Journal, Volume 4 …
Systematic review: the gut microbiome and its potential clinical application in inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …
Guild-based analysis for understanding gut microbiome in human health and diseases
To demonstrate the causative role of gut microbiome in human health and diseases, we first
need to identify, via next-generation sequencing, potentially important functional members …
need to identify, via next-generation sequencing, potentially important functional members …
The diagnostic and prognostic potential of gut bacteria in inflammatory bowel disease
DK Wiredu Ocansey, S Hang, X Yuan, H Qian… - Gut …, 2023 - Taylor & Francis
The gut microbiome serves as a signaling hub that integrates environmental inputs with
genetic and immune signals to influence the host's metabolism and immunity. Gut bacteria …
genetic and immune signals to influence the host's metabolism and immunity. Gut bacteria …
Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease
D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …