European Crohn's and Colitis Organisation topical review on prediction, diagnosis and management of fibrostenosing Crohn's disease

F Rieder, G Latella, F Magro, ES Yuksel… - Journal of Crohn's …, 2016 - academic.oup.com
This ECCO topical review of the European Crohn's and Colitis Organisation [ECCO] focused
on prediction, diagnosis, and management of fibrostenosing Crohn's disease [CD]. The …

Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease

XR Xu, CQ Liu, BS Feng, ZJ Liu - World journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. The exact
etiology and pathology of IBD remain unknown. Available evidence suggests that an …

Polysaccharide based bionanocomposites, properties and applications: A review

R Zafar, KM Zia, S Tabasum, F Jabeen… - International journal of …, 2016 - Elsevier
Bio-nanocomposites, composed of biopolymers and inorganic solids, show dimensions in
the nanometer range (1–100 nm) which can be widely used in variety of areas owing to …

Pectin-coated chitosan–LDH bionanocomposite beads as potential systems for colon-targeted drug delivery

LNM Ribeiro, ACS Alcântara, M Darder… - International journal of …, 2014 - Elsevier
This work introduces results on a new drug delivery system (DDS) based on the use of
chitosan/layered double hydroxide (LDH) biohybrid beads coated with pectin for controlled …

Mechanisms of initiation and progression of intestinal fibrosis in IBD

G Latella, J Di Gregorio, V Flati, F Rieder… - Scandinavian journal …, 2015 - Taylor & Francis
Intestinal fibrosis is a common complication of the inflammatory bowel diseases (IBDs). It
becomes clinically apparent in> 30% of patients with Crohn's disease (CD) and in about 5 …

Cellular and molecular mediators of intestinal fibrosis

IC Lawrance, G Rogler, G Bamias… - Journal of Crohn's …, 2017 - academic.oup.com
Intestinal fibrosis is a major complication of the inflammatory bowel diseases (IBD) and
although inflammation is necessary for its development, it would appear that it plays a minor …

The molecular mechanism of transforming growth factor-β signaling for intestinal fibrosis: a mini-review

SM Yun, SH Kim, EH Kim - Frontiers in pharmacology, 2019 - frontiersin.org
Inflammatory bowel disease is known as the most chronic inflammatory disorder in colon,
which subsequently progresses to intestinal obstruction and fistula formation. Many studies …

[HTML][HTML] Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways

C Sturm, AE Wagner - International Journal of Molecular Sciences, 2017 - mdpi.com
A high consumption of vegetables belonging to the Brassicaceae family has been related to
a lower incidence of chronic diseases including different kinds of cancer. These beneficial …

[HTML][HTML] Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome

N Jacob, JP Jacobs, K Kumagai, CWY Ha… - Mucosal …, 2018 - Elsevier
Tumor necrosis factor-like cytokine 1A (TL1A, TNFSF15) is implicated in inflammatory bowel
disease (IBD), modulating the location and severity of intestinal inflammation and fibrosis …

Clinical predictors of colectomy in patients with ulcerative colitis: systematic review and meta-analysis of cohort studies

CC Dias, PP Rodrigues… - Journal of Crohn's …, 2015 - academic.oup.com
Introduction: Colectomy is a major event that may significantly affect the outcome of
ulcerative colitis (UC) in terms of both quality of life and mortality. This paper aims to identify …