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DNAzyme-based biosensors: Immobilization strategies, applications, and future prospective
Since their discovery almost three decades ago, DNAzymes have been used extensively in
biosensing. Depending on the type of DNAzyme being used, these functional …
biosensing. Depending on the type of DNAzyme being used, these functional …
Challenges and opportunities for develo** electrochemical biosensors with commercialization potential in the point-of-care diagnostics market
There is a plethora of electrochemical biosensors developed for ultrasensitive detection of
clinically relevant biomarkers. However, many of these systems lose their performance in …
clinically relevant biomarkers. However, many of these systems lose their performance in …
Cascade signal amplifying strategy for ultrasensitive detection of tumor biomarker by DNAzyme cleaving mediated HCR
H Chen, J Song, Y Li, D Deng, Y Song, X Zhu… - Sensors and Actuators B …, 2024 - Elsevier
Tumor biomarkers are a kind of important biomolecules for aiding cancer diagnosis and
assessing tumor efficacy, among which alpha-fetoprotein (AFP) is a crucial tumor biomarker …
assessing tumor efficacy, among which alpha-fetoprotein (AFP) is a crucial tumor biomarker …
Functional nucleic acids for pathogenic bacteria detection
D Chang, S Zakaria, S Esmaeili Samani… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Pathogens have long presented a significant threat to human lives, and hence
the rapid detection of infectious pathogens is vital for improving human health. Current …
the rapid detection of infectious pathogens is vital for improving human health. Current …
Electrochemical DNAzyme-based biosensors for disease diagnosis
DNAzyme-based electrochemical biosensors provide exceptional analytical sensitivity and
high target recognition specificity for disease diagnosis. This review provides a critical …
high target recognition specificity for disease diagnosis. This review provides a critical …
DNAzyme-immobilizing microgel magnetic beads enable rapid, specific, culture-free, and wash-free electrochemical quantification of bacteria in untreated urine
Rapid, ultrasensitive, and specific detection and identification of bacteria in unprocessed
clinical specimens is critically needed to enable point-of-care diagnosis of infectious …
clinical specimens is critically needed to enable point-of-care diagnosis of infectious …
DNAzyme‐Functionalized Nanomaterials: Recent Preparation, Current Applications, and Future Challenges
J Jouha, H **ong - Small, 2021 - Wiley Online Library
DNAzyme–nanomaterial bioconjugates are a popular hybrid and have received major
attention for diverse biomedical applications, such as bioimaging, biosensor development …
attention for diverse biomedical applications, such as bioimaging, biosensor development …
DNAzyme-based cascade signal amplification strategy for highly sensitive detection of lead ions in the environment
J Xu, M Liu, W Zhao, S Wang, M Gui, H Li… - Journal of Hazardous …, 2022 - Elsevier
Lead ions are one of many common environmental pollutants, that can cause posing a
serious threat to people's health, thus, their efficient and sensitive detection is important. We …
serious threat to people's health, thus, their efficient and sensitive detection is important. We …
Making target sites in large structured RNAs accessible to RNA-cleaving DNAzymes through hybridization with synthetic DNA oligonucleotides
The 10–23 DNAzyme is one of the most active DNA-based enzymes, and in theory, can be
designed to target any purine-pyrimidine junction within an RNA sequence for cleavage …
designed to target any purine-pyrimidine junction within an RNA sequence for cleavage …
Ratiometric detection of lithium ions in serum and living cells using DNAzyme-assisted hybridization chain reaction
J Wang, Z Feng, J Zhan, Y Shi, J Zhang - Sensors and Actuators B …, 2024 - Elsevier
Lithium, a first-line mood stabilizer for bipolar disorder (BD), presents challenges due to its
narrow therapeutic window (0.6–1.2 mM) and potential side effects in overdose. Hence, it is …
narrow therapeutic window (0.6–1.2 mM) and potential side effects in overdose. Hence, it is …