B‐cell epitope prediction tools are of great medical and commercial interest due to their
practical applications in vaccine development and disease diagnostics. The introduction of …

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is an important public
health problem, occurring mainly in Latin America. The disease has a major social and …

There is no consensus on the diagnostic algorithms for many scenarios of Trypanosoma
cruzi infection, which hinders the establishment of governmental guidelines in endemic and …

Chagas Disease is an important neglected tropical disease caused by Trypanosoma cruzi.
There is no gold standard for diagnosis and commercial serological tests perform poorly in …

Chagas disease, originally a South American endemic health problem, is expanding
worldwide because of people migration. Its main impact is on the cardiovascular system …

Background Trypanosoma cruzi, the agent of Chagas disease, displays a highly structured
population, with multiple strains that can be grouped into 6–7 evolutionary lineages showing …

The detection of pathogen-specific antibodies remains a cornerstone of clinical diagnostics.
Yet, many test exhibit undesirable performance or are completely lacking. Given this, we …

Trypanosoma cruzi is the protozoan unicellular parasite that causes Chagas disease. It can
be transmitted from infected mothers to their babies via the connatal route, thus being able to …

Serological methods should meet the needs of leishmaniasis diagnosis due to their high
sensitivity and specificity, economical and adaptable rapid diagnostic test format, and ease …

Despite nearly a century of research and accounting for the highest disease burden of any
parasitic disease in the Western Hemisphere, Chagas disease (CD) is still a challenging …