[HTML][HTML] Functional acellular matrix for tissue repair

B Wang, T Qinglai, Q Yang, M Li, S Zeng, X Yang… - Materials Today Bio, 2023 - Elsevier
In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Review on porous scaffolds generation process: A tissue engineering approach

MS Flores-Jiménez, A Garcia-Gonzalez… - ACS Applied Bio …, 2023 - ACS Publications
Porous scaffolds have been widely explored for tissue regeneration and engineering in vitro
three-dimensional models. In this review, a comprehensive literature analysis is conducted …

Real‐Time Measurement of Cell Mechanics as a Clinically Relevant Readout of an In Vitro Lung Fibrosis Model Established on a Bioinspired Basement Membrane

A Doryab, MB Taskin, P Stahlhut, J Groll… - Advanced …, 2022 - Wiley Online Library
Lung fibrosis, one of the major post‐COVID complications, is a progressive and ultimately
fatal disease without a cure. Here, an organ‐and disease‐specific in vitro mini‐lung fibrosis …

Harnessing three-dimensional (3D) cell culture models for pulmonary infections: State of the art and future directions

DD Shah, NR Raghani, MR Chorawala, S Singh… - Naunyn-Schmiedeberg's …, 2023 - Springer
Pulmonary infections have been a leading etiology of morbidity and mortality worldwide.
Upper and lower respiratory tract infections have multifactorial causes, which include …

Fabrication Strategies for Bioinspired and Functional Lung‐on‐Chips

A Doryab, J Braig, T Jungst, M Ryma… - Advanced Functional …, 2024 - Wiley Online Library
Abstract Lung‐on‐chips (LoCs) are advanced microsystems designed to culture pulmonary
cells under physiologically relevant conditions, including air–liquid interface, cell stretch …

Exploiting the potential of decellularized extracellular matrix (ECM) in tissue engineering: a review study

P Brouki Milan, F Masoumi, E Biazar… - Macromolecular …, 2024 - Wiley Online Library
While significant progress has been made in creating polymeric structures for tissue
engineering, the therapeutic application of these scaffolds remains challenging owing to the …

[HTML][HTML] Towards a gold standard functional readout to characterize In Vitro lung barriers

A Doryab, O Schmid - European Journal of Pharmaceutical Sciences, 2022 - Elsevier
The development of biomimetic in vitro lung models as an alternative to animal studies is
urgent to improve the predictability of the pharmacokinetics of potential new drugs. For …

Innovative approaches in lung tissue engineering: the role of exosome-loaded bioscaffolds in regenerative medicine

M Torkashvand, L Rezakhani, Z Habibi… - … in Bioengineering and …, 2024 - frontiersin.org
Lung diseases account for over four million premature deaths every year, and experts
predict that this number will increase in the future. The top cause of death globally is …

[HTML][HTML] Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro

A Doryab, M Heydarian, AÖ Yildirim… - Journal of Drug Delivery …, 2023 - Elsevier
Mechanical forces, which are crucial for most downstream signaling pathways in lung (patho-
) physiology, may also regulate the efficacy of drugs. We investigated the role of mechanical …

Develo** human upper, lower, and deep lung airway models: Combining different scaffolds and develo** complex co-cultures

RS Murkar, C Wiese-Rischke… - Journal of Tissue …, 2025 - journals.sagepub.com
Advanced in vitro models are crucial for studying human airway biology. Our objective was
the development and optimization of 3D in vitro models representing diverse airway regions …