Organisms evolve in response to their natural environment. Consideration of natural
ecological parameters are thus of key importance for our understanding of an organism's …

The ability of the nervous system to sense environmental stimuli and to relay these signals to
immune cells via neurotransmitters and neuropeptides is indispensable for effective …

Caenorhabditis elegans must distinguish pathogens from nutritious food sources among the
many bacteria to which it is exposed in its environment. Here we show that a single …

Proper adaptation to environmental perturbations is essential for tissue homeostasis. In the
intestine, diverse environmental cues can be sensed by immune cells, which must balance …

The ability to inherit learned information from parents could be evolutionarily beneficial,
enabling progeny to better survive dangerous conditions. We discovered that, after C …

Multidirectional interactions between the nervous and immune systems have been
documented in homeostasis and pathologies ranging from multiple sclerosis to autism, and …

Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

The nervous system is critical for intestinal homeostasis and function, but questions remain
regarding its impact on gut immune defense. By screening the major neurotransmitters of C …

Distinguishing infectious pathogens from harmless microorganisms is essential for animal
health. The mechanisms used to identify infectious microbes are not fully understood …

Animals face both external and internal dangers: pathogens threaten from the environment,
and unstable genomic elements threaten from within. C. elegans protects itself from …