Targeting ferroptosis in acute kidney injury
L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …
ER stress, the unfolded protein response and osteoclastogenesis: a review
W Huang, Y Gong, L Yan - Biomolecules, 2023 - mdpi.com
Endoplasmic reticulum (ER) stress and its adaptive mechanism, the unfolded protein
response (UPR), are triggered by the accumulation of unfolded and misfolded proteins …
response (UPR), are triggered by the accumulation of unfolded and misfolded proteins …
Mechanisms and cross-talk of regulated cell death and their epigenetic modifications in tumor progression
R He, Y Liu, W Fu, X He, S Liu, D **ao, Y Tao - Molecular Cancer, 2024 - Springer
Cell death is a fundamental part of life for metazoans. To maintain the balance between cell
proliferation and metabolism of human bodies, a certain number of cells need to be removed …
proliferation and metabolism of human bodies, a certain number of cells need to be removed …
Role of caspase family in intervertebral disc degeneration and its therapeutic prospects
L Li, J He, G Zhang, H Chen, Z Luo, B Deng, Y Zhou… - Biomolecules, 2022 - mdpi.com
Intervertebral disc degeneration (IVDD) is a common musculoskeletal degenerative disease
worldwide, of which the main clinical manifestation is low back pain (LBP); approximately …
worldwide, of which the main clinical manifestation is low back pain (LBP); approximately …
[HTML][HTML] Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway
C Fu, Z Qiu, Y Huang, Q Lin, L **, H Tu, J Ye… - Biomedicine & …, 2022 - Elsevier
Endoplasmic reticulum stress (ERS) has been identified to be an important factor leading to
chondrocyte apoptosis in osteoarthritis (OA). Previous studies have confirmed that …
chondrocyte apoptosis in osteoarthritis (OA). Previous studies have confirmed that …
Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy
W Guo, M Wang, Z Yang, D Liu, B Ma, Y Zhao… - European Journal of …, 2023 - Elsevier
Abstract Glucose-regulated protein 78 (GRP78) is one of key endoplasmic reticulum (ER)
chaperone proteins that regulates the unfolded protein response (UPR) to maintain ER …
chaperone proteins that regulates the unfolded protein response (UPR) to maintain ER …
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling
L Ding, T Liao, N Yang, Y Wei, R **ng, P Wu… - Frontiers in …, 2023 - frontiersin.org
Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis
(KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin …
(KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin …
The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling …
Z Zhu, S Gao, C Chen, W Xu, P **ao, Z Chen… - … & Molecular Medicine, 2022 - nature.com
Despite the high prevalence of osteoarthritis (OA) in older populations, disease-modifying
OA drugs (DMOADs) are still lacking. This study was performed to investigate the effects and …
OA drugs (DMOADs) are still lacking. This study was performed to investigate the effects and …
[HTML][HTML] Endoplasmic reticulum stress-mediated cell death in cardiovascular disease
Y An, X Wang, X Guan, P Yuan, Y Liu, L Wei… - Cell Stress and …, 2024 - Elsevier
The endoplasmic reticulum (ER) plays a vital function in maintaining cellular homeostasis.
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …
Ginsenoside compound K ameliorates osteoarthritis by inhibiting the chondrocyte endoplasmic reticulum stress-mediated IRE1α-TXNIP-NLRP3 axis and pyroptosis
Y Tian, X Feng, Z Zhou, S Qin, S Chen… - Journal of Agricultural …, 2023 - ACS Publications
Osteoarthritis (OA) is a common joint disease, and studies have reported that the
endoplasmic reticulum stress (ERS) in chondrocytes caused by the cartilage tissue damage …
endoplasmic reticulum stress (ERS) in chondrocytes caused by the cartilage tissue damage …