Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021‏ - journals.asm.org
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Transmission of SARS-CoV-2: a review of viral, host, and environmental factors

EA Meyerowitz, A Richterman, RT Gandhi… - Annals of internal …, 2021‏ - acpjournals.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 2019 (COVID-19), has spread globally in a few short months …

[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)

A Aleem, AS Ab, AK Slenker - 2021‏ - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern

M McCallum, J Bassi, A De Marco, A Chen, AC Walls… - Science, 2021‏ - science.org
A novel variant of concern (VOC) named CAL. 20C (B. 1.427/B. 1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …

Immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women

YC Ai-ris, K McMahan, J Yu, LH Tostanoski, R Aguayo… - Jama, 2021‏ - jamanetwork.com
Importance Pregnant women are at increased risk of morbidity and mortality from COVID-19
but have been excluded from the phase 3 COVID-19 vaccine trials. Data on vaccine safety …

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

KM Hastie, H Li, D Bedinger, SL Schendel… - Science, 2021‏ - science.org
Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Virology, transmission, and pathogenesis of SARS-CoV-2

M Cevik, K Kuppalli, J Kindrachuk, M Peiris - bmj, 2020‏ - bmj.com
• In the respiratory tract, peak SARS-CoV-2 load is observed at the time of symptom onset or
in the first week of illness, with subsequent decline thereafter, indicating the highest …

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda… - Science, 2020‏ - science.org
The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

F Obermeyer, M Jankowiak, N Barkas, SF Schaffner… - Science, 2022‏ - science.org
Repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased fitness underscores the value of rapid detection and characterization …

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans

YM Loo, PM McTamney, RH Arends… - Science translational …, 2022‏ - science.org
Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines, there remains a need for more prevention and treatment options for individuals …