Molecular interactions underpinning the phenotype of hibernation in mammals
MT Andrews - Journal of Experimental Biology, 2019 - journals.biologists.com
Mammals maintain a constant warm body temperature, facilitating a wide variety of
metabolic reactions. Mammals that hibernate have the ability to slow their metabolism, which …
metabolic reactions. Mammals that hibernate have the ability to slow their metabolism, which …
Hibernation for space travel: Impact on radioprotection
Hibernation is a state of reduced metabolic activity used by some animals to survive in harsh
environmental conditions. The idea of exploiting hibernation for space exploration has been …
environmental conditions. The idea of exploiting hibernation for space exploration has been …
Nature's fat-burning machine: brown adipose tissue in a hibernating mammal
Brown adipose tissue (BAT) is a unique thermogenic tissue in mammals that rapidly
produces heat via nonshivering thermogenesis. Small mammalian hibernators have evolved …
produces heat via nonshivering thermogenesis. Small mammalian hibernators have evolved …
Insights into brown adipose tissue evolution and function from non-model organisms
M Jastroch, R Oelkrug… - Journal of Experimental …, 2018 - journals.biologists.com
Brown adipose tissue (BAT) enables adaptive thermoregulation through heat production that
is catalyzed by mitochondrial uncoupling protein 1 (UCP1). BAT is frequently studied in …
is catalyzed by mitochondrial uncoupling protein 1 (UCP1). BAT is frequently studied in …
Unraveling the big sleep: molecular aspects of stem cell dormancy and hibernation
Tissue-resident stem cells may enter a dormant state, also known as quiescence, which
allows them to withstand metabolic stress and unfavorable conditions. Similarly, hibernating …
allows them to withstand metabolic stress and unfavorable conditions. Similarly, hibernating …
Thermoregulation in hibernating mammals: The role of the “thyroid hormones system”
Hibernation is a unique evolutionary adaptation to conserve energy. During the pre-
hibernation (ie fall) season, a progressive decline in core body temperature and further …
hibernation (ie fall) season, a progressive decline in core body temperature and further …
Plasticity of non-shivering thermogenesis and brown adipose tissue in high-altitude deer mice
High altitude environments challenge small mammals with persistent low ambient
temperatures that require high rates of aerobic heat production in face of low O2 availability …
temperatures that require high rates of aerobic heat production in face of low O2 availability …
Neural circuits of long-term thermoregulatory adaptations to cold temperatures and metabolic demands
The mammalian brain controls heat generation and heat loss mechanisms that regulate
body temperature and energy metabolism. Thermoeffectors include brown adipose tissue …
body temperature and energy metabolism. Thermoeffectors include brown adipose tissue …
Non-shivering thermogenesis is differentially regulated during the hibernation season in Arctic ground squirrels
M Hunstiger, MM Johannsen, SR Oliver - Frontiers in Physiology, 2023 - frontiersin.org
Arctic ground squirrels are small mammals that experience physiological extremes during
the hibernation season. Body temperature rises from 1° C to 40° C during interbout arousal …
the hibernation season. Body temperature rises from 1° C to 40° C during interbout arousal …
[HTML][HTML] MicroRNA expression patterns in the brown fat of hibernating 13-lined ground squirrels
The sequence diversity of microRNAs (miRNAs) allows these potent regulators of mRNA
fate to bind multiple transcripts, giving them the power to inhibit diverse cellular processes …
fate to bind multiple transcripts, giving them the power to inhibit diverse cellular processes …