A lipidome atlas in MS-DIAL 4

H Tsugawa, K Ikeda, M Takahashi, A Satoh… - Nature …, 2020 - nature.com
Abstract We present Mass Spectrometry-Data Independent Analysis software version 4 (MS-
DIAL 4), a comprehensive lipidome atlas with retention time, collision cross-section and …

Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

Y Zheng, Y Liu, J Yang, L Dong, R Zhang, S Tian… - Nature …, 2024 - nature.com
Abstract Characterization and integration of the genome, epigenome, transcriptome,
proteome and metabolome of different datasets is difficult owing to a lack of ground truth …

A review of efforts to improve lipid stability during sample preparation and standardization efforts to ensure accuracy in the reporting of lipid measurements

CZ Ulmer, JP Koelmel, CM Jones, TJ Garrett… - Lipids, 2021 - Wiley Online Library
Lipidomics is a rapidly growing field, fueled by developments in analytical instrumentation
and bioinformatics. To date, most researchers and industries have employed their own …

[HTML][HTML] Systems biology approaches to study lipidomes in health and disease

MA Alves, S Lamichhane, A Dickens… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Lipids have many important biological roles, such as energy storage sources, structural
components of plasma membranes and as intermediates in metabolic and signaling …

Evaluation of lipid quantification accuracy using HILIC and RPLC MS on the example of NIST® SRM® 1950 metabolites in human plasma

M Lange, M Fedorova - Analytical and Bioanalytical Chemistry, 2020 - Springer
Lipidomics analysis for large-scale studies aiming at the identification and quantification of
natural lipidomes is often performed using LC–MS-based data acquisition. However, the …

Plasma lipidome reveals critical illness and recovery from human Ebola virus disease

JE Kyle, KE Burnum-Johnson… - Proceedings of the …, 2019 - National Acad Sciences
Ebola virus disease (EVD) often leads to severe and fatal outcomes in humans with early
supportive care increasing the chances of survival. Profiling the human plasma lipidome …

Merging metabolomics and lipidomics into one analytical run

M Schwaiger, H Schoeny, Y El Abiead, G Hermann… - Analyst, 2019 - pubs.rsc.org
A novel integrated metabolomics/lipidomics workflow is introduced enabling high coverage
of polar metabolites and non-polar lipids within one analytical run. Dual HILIC and RP …

A novel lipidomics workflow for improved human plasma identification and quantification using RPLC-MSn methods and isotope dilution strategies

E Rampler, A Criscuolo, M Zeller, Y El Abiead… - Analytical …, 2018 - ACS Publications
Lipid identification and quantification are essential objectives in comprehensive lipidomics
studies challenged by the high number of lipids, their chemical diversity, and their dynamic …

Shared reference materials harmonize lipidomics across MS-based detection platforms and laboratories

A Triebl, B Burla, J Selvalatchmanan, J Oh, SH Tan… - Journal of lipid …, 2020 - ASBMB
Quantitative MS of human plasma lipids is a promising technology for translation into clinical
applications. Current MS-based lipidomic methods rely on either direct infusion (DI) or …

Quantification of lipids: model, reality, and compromise

S Khoury, C Canlet, MZ Lacroix, O Berdeaux, J Jouhet… - Biomolecules, 2018 - mdpi.com
Lipids are key molecules in various biological processes, thus their quantification is a crucial
point in a lot of studies and should be taken into account in lipidomics development. This …