Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …
Although the previous edition of this classification was published just 5 years earlier, in …
Meningioma: a review of clinicopathological and molecular aspects
Meningiomas are the most the common primary brain tumors in adults, representing
approximately a third of all intracranial neoplasms. They classically are found to be more …
approximately a third of all intracranial neoplasms. They classically are found to be more …
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
Hedgehog signaling mediates embryologic development of the central nervous system and
other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular …
other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular …
An overview of managements in meningiomas
L Zhao, W Zhao, Y Hou, C Wen, J Wang, P Wu… - Frontiers in …, 2020 - frontiersin.org
Meningioma is the most frequent primary tumor of the central nervous system. Important
advances have been achieved in the treatment of meningioma in recent decades. Although …
advances have been achieved in the treatment of meningioma in recent decades. Although …
Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features
Background Meningiomas, the most common primary intracranial tumors, can be separated
into 3 DNA methylation groups with distinct biological drivers, clinical outcomes, and …
into 3 DNA methylation groups with distinct biological drivers, clinical outcomes, and …
Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
Meningiomas are the most common primary intracranial tumors. Treatments for patients with
meningiomas are limited to surgery and radiotherapy, and systemic therapies remain …
meningiomas are limited to surgery and radiotherapy, and systemic therapies remain …
The Role of [68Ga]Ga-DOTA-SSTR PET Radiotracers in Brain Tumors: A Systematic Review of the Literature and Ongoing Clinical Trials
P Palmisciano, G Watanabe, A Conching… - Cancers, 2022 - mdpi.com
Simple Summary [68Ga] Ga-DOTA-SSTR PET imaging has recently been introduced in the
management of patients with brain tumors, mostly meningiomas and pituitary adenomas or …
management of patients with brain tumors, mostly meningiomas and pituitary adenomas or …
H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort
F Behling, C Fodi, I Gepfner-Tuma… - Neuro …, 2021 - academic.oup.com
Background A loss of the trimethylation of lysine 27 of histone H3 (H3K27me3) in
meningioma has been recently suggested as an adjunct to identify subsets of higher risk of …
meningioma has been recently suggested as an adjunct to identify subsets of higher risk of …
WHO grade I meningioma recurrence: identifying high risk patients using histopathological features and the MIB-1 index
Objective: In this study, we identify clinical, radiographic, and histopathologic
prognosticators of overall, early, and post-median recurrence in World Health Organization …
prognosticators of overall, early, and post-median recurrence in World Health Organization …