Revealing protein–lncRNA interaction

F Ferre, A Colantoni… - Briefings in …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …

Methods to study RNA–protein interactions

M Ramanathan, DF Porter, PA Khavari - Nature methods, 2019 - nature.com
Noncoding RNA sequences, including long noncoding RNAs, small nucleolar RNAs, and
untranslated mRNA regions, accomplish many of their diverse functions through direct …

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

H Huang, H Weng, W Sun, X Qin, H Shi, H Wu… - Nature cell …, 2018 - nature.com
Abstract N 6-methyladenosine (m6A) is the most prevalent modification in eukaryotic
messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain …

starBase v2. 0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

JH Li, S Liu, H Zhou, LH Qu, JH Yang - Nucleic acids research, 2014 - academic.oup.com
Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs)(eg lncRNAs,
pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been …

N6-methyladenosine-dependent regulation of messenger RNA stability

X Wang, Z Lu, A Gomez, GC Hon, Y Yue, D Han, Y Fu… - Nature, 2014 - nature.com
Abstract N 6-methyladenosine (m6A) is the most prevalent internal (non-cap) modification
present in the messenger RNA of all higher eukaryotes,. Although essential to cell viability …

YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA

H Shi, X Wang, Z Lu, BS Zhao, H Ma, PJ Hsu, C Liu… - Cell research, 2017 - nature.com
Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and …

Nuclear m6A reader YTHDC1 regulates mRNA splicing

W **ao, S Adhikari, U Dahal, YS Chen, YJ Hao, BF Sun… - Molecular cell, 2016 - cell.com
The regulatory role of N 6-methyladenosine (m 6 A) and its nuclear binding protein YTHDC1
in pre-mRNA splicing remains an enigma. Here we show that YTHDC1 promotes exon …

YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs

IA Roundtree, GZ Luo, Z Zhang, X Wang, T Zhou, Y Cui… - elife, 2017 - elifesciences.org
N 6-methyladenosine (m6A) is the most abundant internal modification of eukaryotic
messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this …

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

N Liu, Q Dai, G Zheng, C He, M Parisien, T Pan - Nature, 2015 - nature.com
RNA-binding proteins control many aspects of cellular biology through binding single-
stranded RNA binding motifs (RBMs),,. However, RBMs can be buried within their local RNA …

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

XL **, BF Sun, LU Wang, W **ao, X Yang, WJ Wang… - Cell research, 2014 - nature.com
Abstract The methyltransferase like 3 (METTL3)-containing methyltransferase complex
catalyzes the N6-methyladenosine (m6A) formation, a novel epitranscriptomic marker; …