RNA self-assembly and RNA nanotechnology

WW Grabow, L Jaeger - Accounts of chemical research, 2014‏ - ACS Publications
Conspectus Nanotechnology's central goal involves the direct control of matter at the
molecular nanometer scale to build nanofactories, nanomachines, and other devices for …

RNA quaternary structure and global symmetry

CP Jones, AR Ferré-D'Amaré - Trends in biochemical sciences, 2015‏ - cell.com
Many proteins associate into symmetric multisubunit complexes. Structural analyses
suggested that, by contrast, virtually all RNAs with complex 3D structures function as …

Protein-guided RNA dynamics during early ribosome assembly

H Kim, SC Abeysirigunawarden, K Chen, M Mayerle… - Nature, 2014‏ - nature.com
The assembly of 30S ribosomes requires the precise addition of 20 proteins to the 16S
ribosomal RNA. How early binding proteins change the ribosomal RNA structure so that …

Composing RNA nanostructures from a syntax of RNA structural modules

C Geary, A Chworos, E Verzemnieks, NR Voss… - Nano …, 2017‏ - ACS Publications
Natural stable RNAs fold and assemble into complex three-dimensional architectures by
relying on the hierarchical formation of intricate, recurrent networks of noncovalent tertiary …

Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing

B Luo, C Zhang, X Ling, S Mukherjee, G Jia, J **e… - Nature Catalysis, 2023‏ - nature.com
The group I self-splicing introns, like other RNAs and RNA–protein complexes, undergo
multiple conformational changes in completing two transesterification reactions that cleave …

Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology

MN Bui, MB Johnson, M Viard… - Therapeutic RNA …, 2021‏ - taylorfrancis.com
RNA nanotechnology employs synthetically modified ribonucleic acid (RNA) to engineer
highly stable nanostructures in one, two, and three dimensions for medical applications …

Fluorescent monitoring of RNA assembly and processing using the split-spinach aptamer

TA Rogers, GE Andrews, L Jaeger… - ACS synthetic …, 2015‏ - ACS Publications
As insights into RNA's many diverse cellular roles continue to be gained, interest and
applications in RNA self-assembly and dynamics remain at the forefront of structural biology …

Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM

S Li, MZ Palo, X Zhang, G Pintilie, K Zhang - Nature Communications, 2023‏ - nature.com
Group I introns are catalytic RNAs that coordinate two consecutive transesterification
reactions for self-splicing. To understand how the group I intron promotes catalysis and …

RNA tectonics (tectoRNA) for RNA nanostructure design and its application in synthetic biology

J Ishikawa, H Furuta, Y Ikawa - Wiley Interdisciplinary Reviews …, 2013‏ - Wiley Online Library
RNA molecules are versatile biomaterials that act not only as DNA‐like genetic materials but
also have diverse functions in regulation of cellular biosystems. RNA is capable of …

Computer Aided Development of Nucleic Acid Applications in Nanotechnologies

M Paloncýová, M Pykal, P Kührová, P Banáš, J Šponer… - Small, 2022‏ - Wiley Online Library
Utilization of nucleic acids (NAs) in nanotechnologies and nanotechnology‐related
applications is a growing field with broad application potential, ranging from biosensing up …