Multi-imaging method to assay the contractile mechanical output of micropatterned human iPSC-derived cardiac myocytes
Rationale: During each beat, cardiac myocytes (CMs) generate the mechanical output
necessary for heart function through contractile mechanisms that involve shortening of …
necessary for heart function through contractile mechanisms that involve shortening of …
Aligned human cardiac syncytium for in vitro analysis of electrical, structural, and mechanical readouts
Human pluripotent stem cell‐derived cardiomyocytes (hPSC‐CMs) have emerged as an
exciting new tool for cardiac research and can serve as a preclinical platform for drug …
exciting new tool for cardiac research and can serve as a preclinical platform for drug …
Two-dimensional culture systems to enable mechanics-based assays for stem cell-derived cardiomyocytes
Well-controlled 2D cell culture systems advance basic investigations in cell biology and
provide innovative platforms for drug development, toxicity testing, and diagnostic assays …
provide innovative platforms for drug development, toxicity testing, and diagnostic assays …
Influence of Remodeled ECM and Co-culture with iPSC-Derived Cardiac Fibroblasts on the Mechanical Function of Micropatterned iPSC-Derived Cardiomyocytes
Introduction In native heart tissue, functions of cardiac fibroblasts (CFs) include synthesis,
remodeling, and degradation of the extracellular matrix (ECM) as well as secreting factors …
remodeling, and degradation of the extracellular matrix (ECM) as well as secreting factors …
Two-dimensional culture systems to investigate mechanical interactions of the cell
Creation of well-controlled two dimensional cell culture systems continues to be important
for the advancement of basic cell biology investigations as well as innovative platforms for …
for the advancement of basic cell biology investigations as well as innovative platforms for …
[BOOK][B] Tissue-engineered Micropatterned Platform to Mature Human PSC-derived Cardiomyocyte
BN Napiwocki - 2019 - search.proquest.com
Human pluripotent stem cell–derived cardiomyocytes (hPSC-CMs) have emerged as
exciting new tools in the field of cardiac research that possess immense therapeutic …
exciting new tools in the field of cardiac research that possess immense therapeutic …