Advances in probing single biomolecules: From DNA bases to glycans
B Hou, T Zhang, H Yang, X Han, L Liu… - Interdisciplinary …, 2023 - Wiley Online Library
Imaging biomolecules in real space is crucial for gaining a comprehensive understanding of
the properties and functions of biological systems at the most fundamental level. Among the …
the properties and functions of biological systems at the most fundamental level. Among the …
Preparation and Characterization of Zn(II)-Stabilized Aβ42 Oligomers
Aβ oligomers are being investigated as cytotoxic agents in Alzheimer's disease (AD).
Because of their transient nature and conformational heterogeneity, the relationship …
Because of their transient nature and conformational heterogeneity, the relationship …
Pyroglutamination-Induced Changes in the Physicochemical Features of a CXCR4 Chemokine Peptide: Kinetic and Structural Analysis
MML Ferreira, SEG de Souza, CC da Silva… - Biochemistry, 2023 - ACS Publications
We investigate the physicochemical effects of pyroglutamination on the QHALTSV-NH2
peptide, a segment of cytosolic helix 8 of the human C–X–C chemokine G-protein-coupled …
peptide, a segment of cytosolic helix 8 of the human C–X–C chemokine G-protein-coupled …
[HTML][HTML] Deep learning-based denoising for unbiased analysis of morphology and stiffness in amyloid fibrils
Understanding the morphology of amyloid fibrils is crucial for comprehending the
aggregation and degradation mechanisms of abnormal proteins implicated in various …
aggregation and degradation mechanisms of abnormal proteins implicated in various …
Maturation-dependent changes in the size, structure and seeding capacity of Aβ42 amyloid fibrils
Many proteins self-assemble to form amyloid fibrils, which are highly organized structures
stabilized by a characteristic cross-β network of hydrogen bonds. This process underlies a …
stabilized by a characteristic cross-β network of hydrogen bonds. This process underlies a …
Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates
In addition to the native state, proteins can form liquid-like condensates, viscoelastic
condensates, such as gels, as well as solid-like condensates, such as amyloid fibrils …
condensates, such as gels, as well as solid-like condensates, such as amyloid fibrils …
Advances in Nanoscale Infrared Spectroscopy to Explore Multiphase Polymeric Systems (Video)| JoVE
R Young, L Tetard - JoVE (Journal of Visualized Experiments), 2023 - jove.com
Multiphase polymeric systems encompass local domains with dimensions that can vary from
a few tens of nanometers to several micrometers. Their composition is commonly assessed …
a few tens of nanometers to several micrometers. Their composition is commonly assessed …