Aging and cancer

L Montégut, C López-Otín, G Kroemer - Molecular Cancer, 2024 - Springer
Aging and cancer exhibit apparent links that we will examine in this review. The null
hypothesis that aging and cancer coincide because both are driven by time, irrespective of …

[HTML][HTML] Stress, epigenetics, and aging: unraveling the intricate crosstalk

Z Wu, J Qu, W Zhang, GH Liu - Molecular Cell, 2024 - cell.com
Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Molecular mechanisms of aging and anti-aging strategies

Y Li, X Tian, J Luo, T Bao, S Wang, X Wu - Cell Communication and …, 2024 - Springer
Aging is a complex and multifaceted process involving a variety of interrelated molecular
mechanisms and cellular systems. Phenotypically, the biological aging process is …

The extracellular matrix integrates mitochondrial homeostasis

H Zhang, CK Tsui, G Garcia, LK Joe, H Wu, A Maruichi… - Cell, 2024 - cell.com
Cellular homeostasis is intricately influenced by stimuli from the microenvironment, including
signaling molecules, metabolites, and pathogens. Functioning as a signaling hub within the …

[HTML][HTML] The translational potential of studying bat immunity

K Baid, AT Irving, N Jouvenet, A Banerjee - Trends in Immunology, 2024 - cell.com
Molecular studies in bats have led to the discovery of antiviral adaptations that may explain
how some bat species have evolved enhanced immune tolerance towards viruses …

Enzyme-mediated green synthesis of glycosaminoglycans and catalytic process intensification

J Zheng, X Lin, H Xu, M Sohail, L Chen… - Biotechnology Advances, 2024 - Elsevier
Glycosaminoglycans (GAGs) are a family of structurally complex heteropolysaccharides that
play pivotal roles in biological functions, including the regulation of cell proliferation, enzyme …

Cross-talk of inflammation and cellular senescence: a new insight into the occurrence and progression of osteoarthritis

Z Han, K Wang, S Ding, M Zhang - Bone Research, 2024 - nature.com
Osteoarthritis (OA) poses a significant challenge in orthopedics. Inflammatory pathways are
regarded as central mechanisms in the onset and progression of OA. Growing evidence …

Hyaluronidase inhibitor delphinidin inhibits cancer metastasis

J McGuire, T Taguchi, G Tombline, V Paige… - Scientific Reports, 2024 - nature.com
Cancer remains a formidable global health challenge, with metastasis being a key
contributor to its lethality. Abundant high molecular mass hyaluronic acid, a major non …

Marine polysaccharides: Biological activities and applications in drug delivery systems

H Geng, M Chen, C Guo, W Wang, D Chen - Carbohydrate Research, 2024 - Elsevier
The ocean is the common home of a large number of marine organisms, including plants,
animals, and microorganisms. Researchers can extract thousands of important bioactive …

Polysaccharides as a promising platform for the treatment of spinal cord injury: A review

Y Yang, R Fan, H Li, H Chen, H Gong, G Guo - Carbohydrate Polymers, 2024 - Elsevier
Spinal cord injury is incurable and often results in irreversible damage to motor function and
autonomic sensory abilities. To enhance the effectiveness of therapeutic substances such as …