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Synthesis and photophysical properties of a novel phthalimide derivative using solvatochromic shift method for the estimation of ground and singlet excited state …
Abstract A novel phthalimide derivative, 2-{4-[(1H-1, 2, 4-triazol-1-yl) methyl] phenyl}-1H–
isoindole-1, 3 (2H)-dione (TMPID) containing an isoindole moiety was synthesized by the …
isoindole-1, 3 (2H)-dione (TMPID) containing an isoindole moiety was synthesized by the …
One‐Pot Generation of Benzynes from Phenols: Formation of Primary Anilines by the Deoxyamination of Phenols
T Ikawa, S Masuda, S Akai - Chemistry–A European Journal, 2020 - Wiley Online Library
Benzynes were selectively generated in situ from phenols and trapped regioselectively with
potassium hexamethyldisilazide to form primary anilines following acidic workup. The direct …
potassium hexamethyldisilazide to form primary anilines following acidic workup. The direct …
Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2)-targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and …
Y Yamamoto, T Hisa, J Arai, Y Saito… - Bioorganic & Medicinal …, 2015 - Elsevier
Nimesulide analogs bearing a methoxy substituent either at the ortho-, meta-or para-position
on the phenyl ring, were designed, synthesized, and evaluated for potential as radioligands …
on the phenyl ring, were designed, synthesized, and evaluated for potential as radioligands …
First Synthesis of Bi‐and Tricyclic α, β‐Unsaturated δ‐Oxacaprolactams from Cyclic Imines via Ring‐Closing Metathesis
M Watzke, K Schulz, K Johannes, P Ullrich, J Martens - 2008 - Wiley Online Library
A new class of α, β‐unsaturated δ‐oxacaprolactams was synthesized from imines as starting
material. The synthetic procedure is based on an acyl chloride addition in the first step …
material. The synthetic procedure is based on an acyl chloride addition in the first step …
Effects of [NaBr] on the Rate of Intramolecular General Base-Assisted Hydrolysis of N-(2′-Hydroxyphenyl)phthalimide in the Presence of Cationic Micelles: Kinetic …
MN Khan, MHR Azri - The Journal of Physical Chemistry B, 2010 - ACS Publications
Pseudofirst-order rate constants for aqueous cleavage of N-(2′-hydroxyphenyl)
phthalimide (1), obtained at 0.001 M NaOH, 2× 10− 4 M 1, 2% v/v CH3CN, and 30° C, show …
phthalimide (1), obtained at 0.001 M NaOH, 2× 10− 4 M 1, 2% v/v CH3CN, and 30° C, show …
Effects of nonionic micelles on the rate of alkaline hydrolysis of N-(2′-methoxyphenyl) phthalimide (1): kinetic and rheometric evidence for a transition from spherical …
Pseudo-first-order rate constants (k obs) for alkaline hydrolysis of N-(2′-methoxyphenyl)
phthalimide (1) decrease nonlinearly with increasing total concentration of nonionic …
phthalimide (1) decrease nonlinearly with increasing total concentration of nonionic …
Kinetics and mechanism of the general base-catalyzed hydrolysis of N-hydroxyphthalimide
WHW Ahmad, YL Sim, M Niyaz Khan - Monatshefte für Chemie-Chemical …, 2013 - Springer
The kinetics and mechanism of hydrolysis of N-hydroxyphthalimide in the presence of
various buffers (dichloroacetic acid, chloroacetic acid, glycine, sodium formate, sodium …
various buffers (dichloroacetic acid, chloroacetic acid, glycine, sodium formate, sodium …
Kinetics and Mechanism of Large Rate Enhancement in the Alkaline Hydrolysis of N′-Morpholino-N-(2′-methoxyphenyl)phthalamide
YL Sim, A Ariffin, MN Khan - The Journal of Organic Chemistry, 2008 - ACS Publications
The apparent second-order rate constant (k OH) for hydroxide-ion-catalyzed conversion of 1
to N-(2′-methoxyphenyl) phthalamate (4) is∼ 103-fold larger than k OH for alkaline …
to N-(2′-methoxyphenyl) phthalamate (4) is∼ 103-fold larger than k OH for alkaline …
Kinetic Evidence for the Formation of Monocationic N,N'-Disubstituted Phthalamide in Tertiary Amine-Catalyzed Hydrolysis of N-Substituted Phthalimides
YL Sim, A Ariffin, MN Khan - The Journal of Organic Chemistry, 2007 - ACS Publications
A kinetic study on the aqueous cleavage of N-(2-methoxyphenyl) phthalimide (1) and N-(2-
hydroxyphenyl) phthalimide (2), under the buffers of N-methylmorpholine, reveals the …
hydroxyphenyl) phthalimide (2), under the buffers of N-methylmorpholine, reveals the …
Kinetics and mechanism of hydrolysis of N‐(2′‐hydroxyphenyl)phthalamic acid (1) and N‐(2′‐methoxyphenyl)phthalamic Acid (2) in a highly alkaline medium
YL Sim, EF Damit, A Ariffin… - International Journal of …, 2009 - Wiley Online Library
A kinetic study on hydrolysis of N‐(2′‐hydroxyphenyl) phthalamic acid (1), N‐(2′‐
methoxyphenyl) phthalamic acid (2), and N‐(2′‐methoxyphenyl) benzamide (3) under a …
methoxyphenyl) phthalamic acid (2), and N‐(2′‐methoxyphenyl) benzamide (3) under a …