High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Organs-on-a-chip module: a review from the development and applications perspective
In recent years, ever-increasing scientific knowledge and modern high-tech advancements
in micro-and nano-scales fabrication technologies have impacted significantly on various …
in micro-and nano-scales fabrication technologies have impacted significantly on various …
Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases
The development of organs-on-chip (OoC) has revolutionized in vitro cell-culture
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
Recent advances for cancer detection and treatment by microfluidic technology, review and update
N Bargahi, S Ghasemali, S Jahandar-Lashaki… - Biological Procedures …, 2022 - Springer
Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …
One-stop microfluidic assembly of human brain organoids to model prenatal cannabis exposure
Prenatal cannabis exposure (PCE) influences human brain development, but it is
challenging to model PCE using animals and current cell culture techniques. Here, we …
challenging to model PCE using animals and current cell culture techniques. Here, we …
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system
C Oleaga, A Riu, S Rothemund, A Lavado… - Biomaterials, 2018 - Elsevier
Regulation of cosmetic testing and poor predictivity of preclinical drug studies has spurred
efforts to develop new methods for systemic toxicity. Current in vitro assays do not fully …
efforts to develop new methods for systemic toxicity. Current in vitro assays do not fully …
Drug toxicity evaluation based on organ-on-a-chip technology: a review
Y Cong, X Han, Y Wang, Z Chen, Y Lu, T Liu, Z Wu… - Micromachines, 2020 - mdpi.com
Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …
[HTML][HTML] Emerging trends in organ-on-a-chip systems for drug screening
New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …
domains, especially from the pharmaceutical industry and healthcare services. Assessment …
Organ-on-a-chip platforms for drug screening and delivery in tumor cells: A systematic review
IM Gonçalves, V Carvalho, RO Rodrigues, D Pinho… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …
Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies
Over the past 15 years, the field of oncology research has witnessed significant progress in
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …