Fertile ground: human endometrial programming and lessons in health and disease

J Evans, LA Salamonsen, A Winship… - Nature Reviews …, 2016 - nature.com
The human endometrium is a highly dynamic tissue that is cyclically shed, repaired,
regenerated and remodelled, primarily under the orchestration of oestrogen and …

The role of inflammation for a successful implantation

N Dekel, Y Gnainsky, I Granot… - American Journal of …, 2014 - Wiley Online Library
Approximately half of all human embryo implantations result in failed pregnancy. Multiple
factors may contribute to this failure, including genetic or metabolic abnormalities of the …

Fertility in women with rheumatoid arthritis: influence of disease activity and medication

J Brouwer, JMW Hazes, JSE Laven… - Annals of the rheumatic …, 2015 - ard.bmj.com
Objectives Many female rheumatoid arthritis (RA) patients attempting to conceive have a
time to pregnancy (TTP) of> 12 months. During this period RA often cannot be treated …

ATP-binding cassette transporters in reproduction: a new frontier

E Bloise, TM Ortiga-Carvalho, FM Reis… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND The transmembrane ATP-binding cassette (ABC) transporters actively efflux
an array of clinically relevant compounds across biological barriers, and modulate …

Etiology and management of recurrent implantation failure: a focus on intra-uterine PBMC-therapy for RIF

G Sheikhansari, Z Pourmoghadam, S Danaii… - Journal of reproductive …, 2020 - Elsevier
Infertility is one of the most common problems among couples worldwide. Recurrent
pregnancy loss, premature ovarian failure, recurrent implantation failure and etc. are …

Harmful and beneficial effects of inflammatory response on reproduction: sterile and pathogen-associated inflammation

Y Negishi, Y Shima, T Takeshita… - Immunological medicine, 2021 - Taylor & Francis
In reproduction, inflammatory processes play important roles in the development of many
pregnancy complications such as preterm labor/birth, recurrent pregnancy loss, recurrent …

Molecular mechanisms of membrane interaction at implantation

LM Davidson, K Coward - Birth Defects Research Part C …, 2016 - Wiley Online Library
Successful pregnancy is dependent upon the implantation of a competent embryo into a
receptive endometrium. Despite major advancement in our understanding of reproductive …

Oxidative stress, inflammatory settings, and microRNA regulation in the recurrent implantation failure patients with metabolic syndrome

G Sheikhansari, MS Soltani‐Zangbar… - American Journal of …, 2019 - Wiley Online Library
Problem Increased oxidative stress (OS) and inflammatory factors in metabolic syndrome
(MS) patients are considered as risk factors for recurrent implantation failure (RIF). The aim …

The embryonic stress response to in vitro culture: insight from genomic analysis

G Cagnone, MA Sirard - Reproduction, 2016 - rep.bioscientifica.com
Recent genomic studies have shed light on the impact of in vitro culture (IVC) on embryonic
homeostasis and the differential gene expression profiles associated with lower …

Evolution of embryo implantation was enabled by the origin of decidual stromal cells in eutherian mammals

AR Chavan, OW Griffith, DJ Stadtmauer… - Molecular biology …, 2021 - academic.oup.com
Mammalian pregnancy evolved in the therian stem lineage, that is, before the common
ancestor of marsupials and eutherian (placental) mammals. Ancestral therian pregnancy …