Spondyloarthritis: update on pathogenesis and management

JD Reveille, FC Arnett - The American journal of medicine, 2005‏ - Elsevier
A great deal of progress has occurred in the past few years in elucidating the causes and
designing new treatments for ankylosing spondylitis and other types of spondyloarthritis. In …

Cytokines and chemokines in uveitis–Is there a correlation with clinical phenotype?

KGJ Ooi, G Galatowicz, VL Calder… - Clinical medicine & …, 2006‏ - clinmedres.org
Uveitis is a general term for intraocular inflammation and includes a large number of clinical
phenotypes. As a group of disorders, it is responsible for 10% of all registered blind patients …

Immunohistological examination of open sacroiliac biopsies of patients with ankylosing spondylitis: detection of tumour necrosis factor α in two patients with early …

RJ Francois, L Neure, J Sieper, J Braun - Annals of the rheumatic diseases, 2006‏ - Elsevier
Objective: To characterise the immunohistological features of sacroiliitis in ankylosing
spondylitis (AS) at different disease stages. Methods: Biopsy samples from sacroiliac joints …

Pathogenesis of ankylosing spondylitis and reactive arthritis

TH Kim, WS Uhm, RD Inman - Current opinion in rheumatology, 2005‏ - journals.lww.com
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Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis

DL Mattey, JC Packham, NB Nixon, L Coates… - Arthritis research & …, 2012‏ - Springer
Introduction The pathology of ankylosing spondylitis (AS) suggests that certain cytokines
and matrix metalloproteinases (MMPs) might provide useful markers of disease activity …

The genetic basis of ankylosing spondylitis

JD Reveille - Current opinion in rheumatology, 2006‏ - journals.lww.com
Nearly half of the susceptibility to ankylosing spondylitis is provided by major
histocompatibility complex genes. Non-major histocompatibility complex genes, most …

The effects of nanocurcumin on Treg cell responses and treatment of ankylosing spondylitis patients: A randomized, double‐blind, placebo‐controlled clinical trial

M Ahmadi, M Hajialilo, S Dolati… - Journal of Cellular …, 2020‏ - Wiley Online Library
Aim Ankylosing spondylitis (AS) is an inflammatory rheumatic disease with increased bone
mass in the main sites of inflammation. Regulatory T (Treg) cells have been reported to …

IL-33 signaling protects from murine oxazolone colitis by supporting intestinal epithelial function

A Waddell, JE Vallance, PD Moore… - Inflammatory bowel …, 2015‏ - academic.oup.com
Background IL-33, a member of the IL-1 cytokine family that signals through ST2, is
upregulated in ulcerative colitis (UC); however, the role of IL-33 in colitis remains unclear. IL …

The pathogenesis of ankylosing spondylitis

MF Shamji, M Bafaquh, E Tsai - Neurosurgical focus, 2008‏ - thejns.org
✓ Ankylosing spondylitis (AS) is a chronic inflammatory disease that can cause significant
functional complications by affecting the sacroiliac joints and axial skeleton. Despite a …

Inhibition of complement retards ankylosing spondylitis progression

C Yang, P Ding, Q Wang, L Zhang, X Zhang, J Zhao… - Scientific reports, 2016‏ - nature.com
Ankylosing spondylitis (AS) is a chronic axial spondyloarthritis (SpA) resulting in back pain
and progressive spinal ankyloses. Currently, there are no effective therapeutics targeting AS …