Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

The burden of comorbidity in people with epilepsy is high. Several diseases, including
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …

Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

abstract The aim of this review was to provide an updated overview of drug-induced
hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms …

During the past decade, major advances have been made in the accurate diagnosis of
severe cutaneous adverse reactions (SCARs) to drugs, management of their manifestations …

When drug reactions resembling allergy occur, they are called drug hypersensitivity
reactions (DHR s) before showing the evidence of either drug‐specific antibodies or T cells …

Abstract Seizures in some 30% to 40% of patients with epilepsy fail to respond to
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …

The epidemiology and aetiology of drug‐induced liver injury (DILI) vary across different
countries and populations. Overall, DILI is rare in the general population but has become …