An overview on the mechanisms and applications of enzyme inhibition-based methods for determination of organophosphate and carbamate pesticides

J Cao, M Wang, H Yu, Y She, Z Cao, J Ye… - Journal of Agricultural …, 2020 - ACS Publications
Acetylcholinesterase inactivating compounds, such as organophosphate (OP) and
carbamate (CM) pesticides, are widely used in agriculture to ensure sustainable production …

Catalytic antibodies in healthy humans and patients with autoimmune and viral diseases

GA Nevinsky, VN Buneva - Journal of cellular and molecular …, 2003 - Wiley Online Library
Antibodies have been first characterized as proteins produced by the immune system solely
for binding other molecules, called antigens, with the goal of eliciting immune response. In …

Natural catalytic antibodies–abzymes

GA Nevinsky, VN Buneva - Catalytic antibodies, 2005 - Wiley Online Library
Abs, antibodies; Abzs, abzymes or catalytically active antibodies; SLE, systemic lupus
erythematosus; HT, Hashimoto's thyroiditis; MS, Multiple sclerosis; ODN …

Nanobody; an old concept and new vehicle for immunotargeting

F Rahbarizadeh, D Ahmadvand… - Immunological …, 2011 - Taylor & Francis
The use of antibodies in cancer therapy has come a long way since the day Paul Ehrlich
described the concept and Kohler and Milstein devised the hybridoma technology to bring …

Human catalytic RNA-and DNA-hydrolyzing antibodies

GA Nevinsky, VN Buneva - Journal of immunological methods, 2002 - Elsevier
In patients with autoimmune diseases, anti-idiotypic antibodies directed to nucleoprotein
complexes, DNA, and enzymes that participate in nucleic acid metabolism may be induced …

Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

DG Ilyushin, IV Smirnov, AA Belogurov Jr… - Proceedings of the …, 2013 - pnas.org
The creation of effective bioscavengers as a pretreatment for exposure to nerve agents is a
challenging medical objective. We report a recombinant method using chemical …

Affinity and catalytic heterogeneity and metal‐dependence of polyclonal myelin basic protein‐hydrolyzing IgGs from sera of patients with systemic lupus …

AM Bezuglova, LP Konenkova… - Journal of Molecular …, 2011 - Wiley Online Library
It was shown using enzyme‐linked immunosorbent assay (ELISA) that titers of antibodies
against human myelin basic protein (hMBP) in systemic lupus erythematosus (SLE) patients …

Autoimmune processes in multiple sclerosis: Production of harmful catalytic antibodies associated with significant changes in the hematopoietic stem cell …

GA Nevinsky - Trending Topics in Multiple Sclerosis, 2016 - books.google.com
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. MS
pathogenesis is not clear. Destruction of myelin by inflammation caused by autoimmune …

Catalytic antibodies in norm and systemic lupus erythematosus

GA Nevinsky - Lupus; Khan, WA, Ed.; InTech: Rijeka, Croatia, 2017 - books.google.com
Systemic lupus erythematosus (SLE) is known as a systemic polyethiologic diffuse
autoimmune disease characterized by connective tissue disorganization and the paramount …

DNA-hydrolysing activity of IgG antibodies from the sera of patients with schizophrenia

EA Ermakov, LP Smirnova… - Open …, 2015 - royalsocietypublishing.org
It is believed that damage to the membranes of brain cells of schizophrenia (SCZ) patients
induces the formation of autoantigens and autoantibodies. Nevertheless, the importance of …