Microbiome 101: studying, analyzing, and interpreting gut microbiome data for clinicians
Advances in technical capabilities for reading complex human microbiomes are leading to
an explosion of microbiome research, leading in turn to intense interest among clinicians in …
an explosion of microbiome research, leading in turn to intense interest among clinicians in …
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine
Microglial function declines during aging. The interaction of microglia with the gut microbiota
has been well characterized during development and adulthood but not in aging. Here, we …
has been well characterized during development and adulthood but not in aging. Here, we …
Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
FJ Ryan, AM Ahern, RS Fitzgerald… - Nature …, 2020 - nature.com
Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota
with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics …
with distribution of inflammation. We report microbiota, host transcriptomics, epigenomics …
High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis
The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and
fungi,. Although the composition of bacterial constituents has been linked to immune …
fungi,. Although the composition of bacterial constituents has been linked to immune …
phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data
Background The analysis of microbial communities through DNA sequencing brings many
challenges: the integration of different types of data with methods from ecology, genetics …
challenges: the integration of different types of data with methods from ecology, genetics …
Microbiota engraftment after faecal microbiota transplantation in obese subjects with type 2 diabetes: a 24-week, double-blind, randomised controlled trial
Objective The impact of faecal microbiota transplantation (FMT) on microbiota engraftment in
patients with metabolic syndrome is uncertain. We aimed to study whether combining FMT …
patients with metabolic syndrome is uncertain. We aimed to study whether combining FMT …
Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn's disease
Intestinal microbial dysbiosis is associated with Crohn's disease (CD). However, the
mechanisms leading to the chronic mucosal inflammation that characterizes this disease …
mechanisms leading to the chronic mucosal inflammation that characterizes this disease …
Bile acids drive the newborn's gut microbiota maturation
Following birth, the neonatal intestine is exposed to maternal and environmental bacteria
that successively form a dense and highly dynamic intestinal microbiota. Whereas the effect …
that successively form a dense and highly dynamic intestinal microbiota. Whereas the effect …
Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults
We assessed the gut microbiota of 90 American young adults, comparing 43 participants
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
with major depressive disorder (MDD) and 47 healthy controls, and found that the MDD …
Brief Report: Dialister as a Microbial Marker of Disease Activity in Spondyloarthritis
RY Tito, H Cypers, M Joossens, G Varkas… - Arthritis & …, 2017 - Wiley Online Library
Objective Dysbiosis of the intestinal microbiota has been widely established in inflammatory
bowel disease (IBD). There is significant clinical and genetic overlap between …
bowel disease (IBD). There is significant clinical and genetic overlap between …