[HTML][HTML] Kaempferol: Paving the path for advanced treatments in aging-related diseases

MS Hussain, ASA Altamimi, M Afzal, WH Almalki… - Experimental …, 2024 - Elsevier
Aging-related diseases (ARDs) are a major global health concern, and the development of
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …

“Bone-SASP” in skeletal aging

CL Fang, B Liu, M Wan - Calcified Tissue International, 2023 - Springer
Senescence is a complex cell state characterized by stable cell cycle arrest and a unique
secretory pattern known as the senescence-associated secretory phenotype (SASP). The …

Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - Nutrients, 2023 - mdpi.com
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …

A Comparison of the Antiosteoporotic Effects of Cornelian Cherry (Cornus mas L.) Extracts from Red and Yellow Fruits Containing Different Constituents of …

E Park, T Sozański, CG Lee… - Oxidative Medicine …, 2022 - Wiley Online Library
Background and aims. Bone remodeling in which old or damaged bone cells are removed
by osteoclasts, and new bone cells are developed by osteoblasts is a key target for …

[HTML][HTML] Bioactive Compounds from Propolis on Bone Homeostasis: A Narrative Review

V Bertolucci, AF Ninomiya, GB Longato, LO Kaneko… - Antioxidants, 2025 - mdpi.com
This narrative review explores the potential effects of Propolis and its bioactive compounds
on bone health. Propolis, a resinous product collected by bees, is renowned for its …

Qizhi Kebitong Formula Ameliorates Streptozocin‐Induced Diabetic Osteoporosis through Regulating the PI3K/Akt/NF‐κB Pathway

L Tian, L Ding, G Wang, Y Guo, Y Zhao… - BioMed Research …, 2022 - Wiley Online Library
Background. Diabetic osteoporosis (DOP) is a progressive osteoblast dysfunction induced
by high glucose, which has negative impacts on bone homeostasis. Qizhi Kebitong formula …

Research on the Mechanism of Asperosaponin VI for Treating Recurrent Spontaneous Abortion by Bioinformatics Analysis and Experimental Validation

B **a, P Zhang, Y Lai, S Cui, Z Chen… - Evidence‐Based …, 2022 - Wiley Online Library
Asperosaponin VI (AS6), as the quality marker of Dipsaci Radix, is verified to exert
therapeutic effect on alleviating recurrent spontaneous abortion (RSA). However, due to the …

Zuo Gui Wan Promotes Osteogenesis via PI3K/AKT Signaling Pathway: Network Pharmacology Analysis and Experimental Validation

S Yang, B Zhang, Y Wang, Z Liu, B Qiao, J Xu… - Current Medical …, 2023 - Springer
Objective Osteogenesis is vitally important for bone defect repair, and Zuo Gui Wan (ZGW) is
a classic prescription in traditional Chinese medicine (TCM) for strengthening bones …

Transcriptomics-based Exploration of the Mechanism of Kaempferol in the Treatment of Osteoporosis in Ovariectomized Rats

Z Pu, C Zhang, Q Yan, Z Liang, ZW Xu… - Natural Product …, 2024 - journals.sagepub.com
Objective: We explore the pharmacodynamic targets of kaempferol in treating osteoporosis
using transcriptomics and animal experiment. Methods: Firstly, we constructed an …

[PDF][PDF] Bioactivity, Molecular Mechanism, and Targeted Deliv-ery of Flavonoids for Bone Loss. Nutrients 2023, 15, 919

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - 2023 - researchgate.net
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …