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Sex and gender differences in myocarditis and dilated cardiomyopathy: An update
DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …
Mechanistic pathways of sex differences in cardiovascular disease
V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2017 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
Sex differences in myocardial and vascular aging
It is well known that cardiovascular disease manifests differently in women and men. The
underlying causes of these differences during the aging lifespan are less well understood …
underlying causes of these differences during the aging lifespan are less well understood …
Estrogen-related mechanisms in sex differences of hypertension and target organ damage
AR Sabbatini, G Kararigas - Biology of sex differences, 2020 - Springer
Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ
damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is …
damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is …
Menopause-Related Estrogen Decrease and the Pathogenesis of HFpEF: JACC Review Topic of the Week
AR Sabbatini, G Kararigas - Journal of the American College of Cardiology, 2020 - jacc.org
Heart failure (HF) is a complex condition affecting> 40 million people worldwide. It is defined
by failure of the heart to pump (HF with reduced ejection fraction) or by the failure of the …
by failure of the heart to pump (HF with reduced ejection fraction) or by the failure of the …
Sex in basic research: concepts in the cardiovascular field
R Ventura-Clapier, E Dworatzek… - Cardiovascular …, 2017 - academic.oup.com
Women and men, female and male animals and cells are biologically different, and
acknowledgement of this fact is critical to advancing medicine. However, incorporating …
acknowledgement of this fact is critical to advancing medicine. However, incorporating …
Decellularized tissues as platforms for in vitro modeling of healthy and diseased tissues
Biomedical engineers are at the forefront of develo** novel treatments to improve human
health, however, many products fail to translate to clinical implementation. In vivo pre-clinical …
health, however, many products fail to translate to clinical implementation. In vivo pre-clinical …
Widespread sex dimorphism in aging and age-related diseases
Although aging is a conserved phenomenon across evolutionary distant species, aspects of
the aging process have been found to differ between males and females of the same …
the aging process have been found to differ between males and females of the same …
Matters of the heart: Cellular sex differences
Nearly all cardiovascular diseases show sexual dimorphisms in prevalence, presentation,
and outcomes. Until recently, most clinical trials were carried out in males, and many animal …
and outcomes. Until recently, most clinical trials were carried out in males, and many animal …
A framework for develo** sex-specific engineered heart models
The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …