Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …

Systemic lupus erythematosus (SLE, lupus) is a debilitating, multisystem autoimmune
disease that can affect any organ in the body. The disease is characterized by circulating …

Background Amongst risk alleles associated with late-onset Alzheimer's disease (AD), those
that converged on the regulation of microglia activity have emerged as central to disease …

Alzheimer's disease (AD) is characterized by accumulation of misfolded proteins. Genetic
studies implicate microglia, brain-resident phagocytic immune cells, in AD pathogenesis. As …

Alzheimer's disease (AD) is the most common neurodegenerative disease and the most
common cause of dementia. Among various pathophysiological aspects, microglia are …

Introduction Many pathologies, including cancer, have been associated with aberrant
phosphorylation-mediated signaling networks that drive altered cell proliferation, migration …

Most human Siglecs (sialic acid binding immunoglobulin-like lectins) are expressed on the
surfaces of overlap** subsets of immune cells, and most carry immunoreceptor tyrosine …

Microglia are resident myeloid cells in the central nervous system (CNS) with a unique
developmental origin, playing essential roles in develo** and maintaining the CNS …

Siglecs (Sialic acid-binding immunoglobulin-type lectins) are I-type lectins that bind with
sialic acid ligands (Sia). Most are expressed on the surface of leukocytes and are involved in …

Alzheimer's disease (AD) is a form of dementia characterized by amyloid-β plaques and tau
neurofibrillary tangles that progressively disrupt neural circuits in the brain. The signaling …