Vitamin K, a cofactor for the γ-glutamyl carboxylase enzyme, is required for the post-
translational activation of osteocalcin and matrix Gla protein, which play a key role in bone …

Fragility fracture is a worldwide problem and a main cause of disability and impaired quality
of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or …

Vitamin K (VK), a fat-soluble vitamin, is well known as an anticoagulant in the clinic. It is
essential for the post-translational activation of VK-dependent proteins (VKDPs) because …

Aims Evidence on the association between the risk of new-onset osteoporosis and oral
anticoagulants remains controversial. We aimed to compare the risk of osteoporosis …

Objective The three direct oral anticoagulants (DOAC), rivaroxaban, apixaban and
dabigatran have been associated with lower risks of fractures compared to warfarin …

Background: Anticoagulants (AC) are among the most often prescribed drugs in the world.
Data regarding ACs' effect on the osseointegration of dental implants is lacking. Purpose …

Background The trabecular bone score (TBS) indirectly estimates bone quality and predicts
low-impact fractures independently of bone mineral density (BMD). However, there is still a …

Proteins C and S are vitamin K-dependent anticoagulative factors that also exert a
significant influence on bone quality. Clinical studies have linked the deficiency of proteins C …

Sodium dehydroacetate (DHA-Na) is a fungicidal preservative widely used in food and
animal feed. DHA-Na can induce coagulation disorders in rats and poultry by inhibiting …

Purpose This large-scale retrospective study aimed to examine the long-term effect of
antiplatelet and anticoagulant medications intake on dental implant treatment outcome …