Background: Withania somnifera (WS), also known as Ashwagandha, is commonly used in
Ayurveda and other traditional medicine systems. WS has seen an increase in worldwide …

Natural products and their semisynthetic derivatives continue to be an important source of
potential drug leads. Natural products and their analogues structures possess the …

The mechanisms by which cells adapt to proteotoxic stress are largely unknown, but are key
to understanding how tumor cells, particularly in vivo, are largely resistant to proteasome …

As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …

Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …

Withaferin A (WA), a manifold studied, C28-steroidal lactone withanolide found in Withania
somnifera. Given its unique beneficial effects, it has gathered attention in the era of modern …

The identification of bioactive molecules that have potential to interrupt carcinogenesis
continues to garner research interest. In particular, molecules that have dietary origin are …

Context: Cancer, being a cause of death for major fraction of population worldwide, is one of
the most studied diseases and is being investigated for the development of new …

Background: Withania somnifera (WS), a popular medicinal plant of the Solanaceae family,
contains active ingredients with antioxidant, anti-inflammatory, immunomodulatory, and anti …

Withanolides, and in particular extracts from Withania somnifera, have been used for over
3,000 years in traditional Ayurvedic and Unani Indian medical systems as well as within …